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(8S,15S)-DIHETE

Product Name
(8S,15S)-DIHETE
CAS No.
80234-65-7
Chemical Name
(8S,15S)-DIHETE
Synonyms
(8S,15S)-DIHETE;8(S),15(S)-DiHETE (Z, E, Z, E);8(S),15(S)DiHETE,8(S),15(S) DiHETE;(8S,15S)-dihydroxy-(5Z,9E,11Z,13E)-*eicosatetraen;(8S,15S)-DIHYDROXY-(5Z,9E,11Z,13E)-EICOS ATETRAENOI;8(S),15(S)-DIHYDROXYEICOSA-5Z,9E,11Z,13E-TETRAENOIC ACID;(8S,15S)-DIHYDROXY-(5Z,9E,11Z,13E)-EICOSATETRAENOIC ACID;5,9,11,13-Eicosatetraenoic acid, 8,15-dihydroxy-, (5Z,8S,9E,11Z,13E,15S)-
CBNumber
CB4455802
Molecular Formula
C20H32O4
Formula Weight
336.47
MOL File
80234-65-7.mol
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(8S,15S)-DIHETE Property

storage temp. 
−20°C
solubility 
DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
form 
Colorless liquid.
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Safety

Hazard Codes 
F,Xi
Risk Statements 
11-36/37/38
Safety Statements 
16-26-36
RIDADR 
UN 1170 3/PG 2
WGK Germany 
1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
35370
Product name
8(S),15(S)-DiHETE
Purity
≥98%
Packaging
25μg
Price
$95
Updated
2024/03/01
Cayman Chemical
Product number
35370
Product name
8(S),15(S)-DiHETE
Purity
≥98%
Packaging
50μg
Price
$179
Updated
2024/03/01
Cayman Chemical
Product number
35370
Product name
8(S),15(S)-DiHETE
Purity
≥98%
Packaging
100μg
Price
$337
Updated
2024/03/01
TRC
Product number
D446408
Product name
8(S),15(S)-DiHETE(Z,E,Z,E)
Packaging
100μg
Price
$210
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BRS0000005
Product name
(8S,15S)-DIHYDROXY-(5Z,9E,11Z,13E)-EICOSATETRAENOIC ACID
Purity
95.00%
Packaging
5MG
Price
$502.16
Updated
2021/12/16
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(8S,15S)-DIHETE Chemical Properties,Usage,Production

Description

8(S),15(S)-DiHETE is formed when 15(S)-HETE is subjected to further oxidation by 15-LO. It causes eosinophil chemotaxis with an ED50 value of 1.5 μM but is not chemotactic for neutrophils. 8(S),15(S)-DiHETE antagonizes the hyperalgesic activity of 8(R),15(S)-DiHETE and LTB4 in the rat hind paw pain model.

Uses

8(S),15(S)-DiHETE (Z, E, Z, E) is a novel dioxygenation product of arachidonic acid.

Definition

ChEBI: 8(S),15(S)-DiHETE is ab 8,15-DiHETE that is derived from (5Z,9E,11Z,13E)-icosatetraenoic acid and has (8S,15S)-stereochemistry. It has a role as a human xenobiotic metabolite and a mouse metabolite. It is functionally related to an arachidonic acid. It is a conjugate acid of an 8(S),15(S)-DiHETE(1-).

(8S,15S)-DIHETE Preparation Products And Raw materials

Raw materials

Preparation Products

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(8S,15S)-DIHETE Suppliers

China 11 Germany 2 Switzerland 1 United Kingdom 1 United States 7 Global 22
SIGMA-RBI
Tel
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Fax
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Country
Switzerland
ProdList
6896
Advantage
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80234-65-7, (8S,15S)-DIHETERelated Search:

8(S),15(S)-DIHETE 8(R),15(S)-DIHETE 5(S), 15(S)-DIHETE 5(S),15(S)-DIHETE [1-14C] 8(S),15(S)-DIHETE [1-14C] 1.3.7-OCTATRIENE 1,5-HEPTADIEN-4-OL (8S,15S)-DIHETE

  • (8S,15S)-DIHETE
  • (8S,15S)-DIHYDROXY-(5Z,9E,11Z,13E)-EICOSATETRAENOIC ACID
  • 8(S),15(S)-DIHYDROXYEICOSA-5Z,9E,11Z,13E-TETRAENOIC ACID
  • (8S,15S)-dihydroxy-(5Z,9E,11Z,13E)-*eicosatetraen
  • (8S,15S)-DIHYDROXY-(5Z,9E,11Z,13E)-EICOS ATETRAENOI
  • 8(S),15(S)-DiHETE (Z, E, Z, E)
  • 5,9,11,13-Eicosatetraenoic acid, 8,15-dihydroxy-, (5Z,8S,9E,11Z,13E,15S)-
  • 8(S),15(S)DiHETE,8(S),15(S) DiHETE
  • 80234-65-7
  • Biochemicals and Reagents
  • BioChemical
  • Fatty Acids
  • Unsaturated fatty acids and derivatives
  • Lipids
  • Hydroxy fatty acids
  • Polyunsaturated