ChemicalBook > CAS DataBase List > (4-METHOXY-2-NITRO-PHENYL)-ACETIC ACID

(4-METHOXY-2-NITRO-PHENYL)-ACETIC ACID

Product Name
(4-METHOXY-2-NITRO-PHENYL)-ACETIC ACID
CAS No.
20876-30-6
Chemical Name
(4-METHOXY-2-NITRO-PHENYL)-ACETIC ACID
Synonyms
4-Methoxy-2-nitro-benzeneacetic acid;(2-Nitro-4-Methoxyphenyl)acetic acid;Benzeneacetic acid, 4-methoxy-2-nitro-;(4-METHOXY-2-NITRO-PHENYL)-ACETIC ACID;2-(4-Methoxy-2-nitrophenyl)acetic acid
CBNumber
CB4460794
Molecular Formula
C9H9NO5
Formula Weight
211.17
MOL File
20876-30-6.mol
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(4-METHOXY-2-NITRO-PHENYL)-ACETIC ACID Property

storage temp. 
Sealed in dry,Room Temperature
Appearance
Yellow to brown Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M493065
Product name
2-(4-Methoxy-2-nitrophenyl)aceticAcid
Packaging
10mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
8789AH
Product name
(4-Methoxy-2-nitro-phenyl)-aceticacid
Packaging
250mg
Price
$189
Updated
2021/12/16
AK Scientific
Product number
8789AH
Product name
(4-Methoxy-2-nitro-phenyl)-aceticacid
Packaging
5g
Price
$651
Updated
2021/12/16
AK Scientific
Product number
8789AH
Product name
(4-Methoxy-2-nitro-phenyl)-aceticacid
Packaging
25g
Price
$2456
Updated
2021/12/16
Ambeed
Product number
A679605
Product name
2-(4-Methoxy-2-nitrophenyl)aceticacid
Purity
95%
Packaging
250mg
Price
$99
Updated
2021/12/16
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(4-METHOXY-2-NITRO-PHENYL)-ACETIC ACID Chemical Properties,Usage,Production

Synthesis

10565-15-8

20876-30-6

Diethyl 4-methoxy-2-nitrophenylmalonate (1.1 g, 36 mmol) was used as a raw material, which was dissolved in 5 mL of 6N hydrochloric acid solution and the reaction was carried out at reflux under stirring conditions for 13 hours. After completion of the reaction, the reaction mixture was cooled to room temperature and the precipitated brown precipitate was collected by filtration and washed with deionized water. The resulting precipitate was dissolved in 1.5 mL of 2N sodium hydroxide solution and subsequently extracted with 1 mL of ethyl acetate. The aqueous layer was mixed with 0.1 g Darco-G60 and refluxed for thermal filtration. The filtrate was acidified with 0.5 mL of 6N sulfuric acid and cooled in a refrigerator. The precipitated tan precipitate was collected by vacuum filtration, washed with deionized water and dried under vacuum to give 0.6 g of 4-methoxy-2-nitrophenylacetic acid in 82% yield.

References

[1] Patent: WO2008/101979, 2008, A1. Location in patent: Page/Page column 72-73
[2] Patent: US2004/186160, 2004, A1. Location in patent: Page/Page column 23-24

(4-METHOXY-2-NITRO-PHENYL)-ACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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