ChemicalBook > CAS DataBase List > NAFTOPIDIL DIHYDROCHLORIDE

NAFTOPIDIL DIHYDROCHLORIDE

Product Name: NAFTOPIDIL DIHYDROCHLORIDE
CAS No.: 57149-08-3
Chemical Name: NAFTOPIDIL DIHYDROCHLORIDE
Synonyms: KT-611 2HCl;Naftopidil HCL;NAFTOPIDIL 2HCL;piperazin-1-yl);Naftopidil DiHCl;1-(4-(2-Methoxyphenyl);KT-611 DIHYDROCHLORIDE;-3-(naphthalen-1-yloxy);propan-2-ol dihydrochloride;NAFTOPIDIL DIHYDROCHLORIDE USP/EP/BP
CBNumber: CB4465739
Molecular Formula: C24H30Cl2N2O3
Formula Weight: 465.41
MOL File: 57149-08-3.mol

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NAFTOPIDIL DIHYDROCHLORIDE Property

Melting point:: 212-213°
storage temp.: Sealed in dry,Room Temperature
solubility: methanol: >10 mg/mL
form: solid
color: white

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Safety

WGK Germany: 3
RTECS: TL9336500

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: N213500
Product name: NaftopidilDihydrochloride
Packaging: 1g
Price: $875
Updated: 2021/12/16

AK Scientific

Product number: F011
Product name: Naftopidildihydrochloride
Packaging: 100mg
Price: $149.5
Updated: 2021/12/16

ApexBio Technology

Product number: B1366
Product name: NaftopidilDiHCl
Packaging: 10g
Price: $172
Updated: 2021/12/16

Ambeed

Product number: A127685
Product name: NaftopidilDiHydrochloride
Purity: 97%
Packaging: 1mg
Price: $7
Updated: 2021/12/16

BLDpharm

Product number: BD143116
Product name: NaftopidilDiHydrochloride
Purity: 97%
Packaging: 5mg
Price: $19
Updated: 2021/12/16

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NAFTOPIDIL DIHYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

A α-1-Adrenergic receptor antagonist, antihypertensive.

Uses

Antihypertensive;Alpha1 agonist

in vivo

Naftopidil dihydrochloride (10 mg/kg; p.o; daily; for 28 days) decreases microvessel density (MVD) in E9+PrSC tumors mice model^[2].

Animal Model:	Male athymic mice(7-8 weeks), with E9+PrSC xenograft^[2]
Dosage:	10 mg/kg
Administration:	Oral administration, daily, for 28 days
Result:	Decreased tumor weights.

IC 50

Alpha-1A adrenergic receptor: 3.7 nM (Ki); Alpha-1B adrenergic receptor: 20 nM (Ki); Alpha-1D adrenergic receptor: 1.2 (Ki)

NAFTOPIDIL DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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NAFTOPIDIL DIHYDROCHLORIDE Suppliers

Canada 2 China 77 Germany 1 India 4 Switzerland 1 United Kingdom 2 United States 15 USA 1 Global 103

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View Lastest Price from NAFTOPIDIL DIHYDROCHLORIDE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Naftopidil dihydrochloride 57149-08-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 500 MT
Release date: 2020-05-11

Career Henan Chemical Co

Product: Naftopidil 57149-08-3
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 1ton
Release date: 2020-01-10

57149-08-3, NAFTOPIDIL DIHYDROCHLORIDERelated Search:

AR-13324 (mesylate)

NAFTOPIDIL 2HCL

4-(2-METHOXYPHENYL)-A-[(1-NAPHTHALENYLOXY)METHYL]-1-PIPERAZINEETHANOL, DIHYDROCHLORIDE

4-(2-METHOXYPHENYL)-ALPHA-([1-NAPHTHALENYLYOXY]METHYL)-1-PIPERAZINEETHANOL DIHYDROCHLORIDE

KT-611 DIHYDROCHLORIDE

4-(2-Methoxyphenyl)-a-[(1-naphthalenyloxy)methyl]-1-piperazineethanol,2HCl

Naftopidil HCL

3-[(4-methylpiperazin-1-yl)methyl]quinazolin-4-one dihydrochloride

1-[4-(2-Methoxyphenyl)-1-piperazinyl]-3-(1-naphthoxy)-2-propanol dihydrochloride

1-(4-(2-methoxyphenyl)piperazin-1-yl)-3-(naphthalen-1-yloxy)propan-2-ol dihydrochloride

Naftopidil DiHCl

1-(4-(2-Methoxyphenyl)

-3-(naphthalen-1-yloxy)

piperazin-1-yl)

propan-2-ol dihydrochloride

KT-611 2HCl

NAFTOPIDIL DIHYDROCHLORIDE USP/EP/BP

1-Piperazineethanol, 4-(2-methoxyphenyl)-α-[(1-naphthalenyloxy)methyl]-, hydrochloride (1:2)

Naftopidil dihydrochloride, 10 mM in DMSO

57149-08-3

57419-08-3

C24H28N2O32HCl

Inhibitors

Intermediates & Fine Chemicals

Pharmaceuticals

Flivas, KT-611, Avishot