JI051

Product Name: JI051
CAS No.: 2234281-75-3
Chemical Name: JI051
Synonyms: JI051;JI051 (JI 051;JI051;JI 051;JI-051;(2E)-N-[2-(2-ethoxyphenyl)ethyl]-3-(7-methoxy-1H-indol-3-yl)prop-2-enamide;2-Propenamide, N-[2-(2-ethoxyphenyl)ethyl]-3-(7-methoxy-1H-indol-3-yl)-, (2E)-
CBNumber: CB44668071
Molecular Formula: C22H24N2O3
Formula Weight: 364.44
MOL File: 2234281-75-3.mol

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JI051 Property

Boiling point:: 635.6±55.0 °C(Predicted)
Density: 1.187±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:125.0(Max Conc. mg/mL);342.99(Max Conc. mM)
form: Solid
pka: 14.34±0.46(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0063785
Product name: JI051
Purity: >98.0%
Packaging: 5mg
Price: $450
Updated: 2021/12/16

ChemScene

Product number: CS-0063785
Product name: JI051
Purity: >98.0%
Packaging: 10mg
Price: $750
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611315
Product name: JI051
Purity: >98%
Packaging: 100mg
Price: $1133.9
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611315
Product name: JI051
Purity: >98%
Packaging: 250mg
Price: $1949.9
Updated: 2021/12/16

ChemScene

Product number: CS-0063785
Product name: JI051
Purity: >98.0%
Packaging: 50mg
Price: $2250
Updated: 2021/12/16

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JI051 Chemical Properties,Usage,Production

Uses

JI051 is a stabilizer for the Hes1-PHB2 interaction. JI051 interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2), induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1. Anti-cancer activity[1].

References

[1] Perron A, et al. Small-molecule screening yields a compound that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone. J Biol Chem. 2018 May 25;293(21):8285-8294. DOI:10.1074/jbc.RA118.002316

JI051 Preparation Products And Raw materials

Raw materials

Preparation Products

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JI051 Suppliers

China 25 United States 5 Global 30

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
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Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32470
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InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Fax: QQ 3610331285
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Country: China
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Shanghai hongqu biomedical technology co. LTD

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Country: China
ProdList: 5132
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Chunchuang (Wuhan) Technology Co., Ltd

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Email: yutianchun2007@126.com
Country: China
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Zhengzhou convergence chemical co., LTD

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Beijing Jin Ming Biotechnology Co., Ltd.

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Hubei Kele Fine Chemical Co., Ltd

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Fax: 027-59101668
Email: 2881924765@qq.com
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2234281-75-3, JI051Related Search:

JI051

JI051 (JI 051

JI051;JI 051;JI-051

2-Propenamide, N-[2-(2-ethoxyphenyl)ethyl]-3-(7-methoxy-1H-indol-3-yl)-, (2E)-

(2E)-N-[2-(2-ethoxyphenyl)ethyl]-3-(7-methoxy-1H-indol-3-yl)prop-2-enamide

2234281-75-3