AZ-1

Product Name: AZ-1
CAS No.: 2165322-94-9
Chemical Name: AZ-1
Synonyms: USP25/28 inhibitor AZ1;USP25 and 28 inhibitor AZ-1;AZ-1;AZ-1;AZ 1;AZ1;AZ1 USP25/28 inhibitor;USP25/28 inhibitor AZ1, 10 mM in DMSO;2-((5-bromo-2-((4-fluoro-3-(trifluoromethyl)benzyl)oxy)benzyl)amino)ethanol;2-((5-Bromo-2-((4-fluoro-3-(trifluoromethyl)benzyl)oxy)benzyl)amino)ethan-1-ol;Ethanol, 2-[[[5-bromo-2-[[4-fluoro-3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]amino]-;Deubiquitinase,USP-25/28 inhibitor AZ1,USP25/28 inhibitor AZ1,inhibit,AZ 1,Inhibitor,AZ-1,DUBs
CBNumber: CB44668637
Molecular Formula: C17H16BrF4NO2
Formula Weight: 422.21
MOL File: 2165322-94-9.mol

More

Less

AZ-1 Property

Boiling point:: 478.5±40.0 °C(Predicted)
Density: 1.488±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: ≥ 250 mg/mL (592.12 mM); Water: < 0.1 mg/mL (insoluble)
form: Solid
pka: 14.74±0.10(Predicted)
color: White to off-white

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-0065552
Product name: USP25/28inhibitorAZ1
Purity: 98.10%
Packaging: 5mg
Price: $150
Updated: 2021/12/16

ChemScene

Product number: CS-0065552
Product name: USP25/28inhibitorAZ1
Purity: 98.10%
Packaging: 10mg
Price: $250
Updated: 2021/12/16

ChemScene

Product number: CS-0065552
Product name: USP25/28inhibitorAZ1
Purity: 98.10%
Packaging: 25mg
Price: $500
Updated: 2021/12/16

ChemScene

Product number: CS-0065552
Product name: USP25/28inhibitorAZ1
Purity: 98.10%
Packaging: 50mg
Price: $850
Updated: 2021/12/16

ChemScene

Product number: CS-0065552
Product name: USP25/28inhibitorAZ1
Purity: 98.10%
Packaging: 100mg
Price: $1450
Updated: 2021/12/16

More

Less

AZ-1 Chemical Properties,Usage,Production

Biological Activity

AZ1 is a potent and selective dual USP25 & USP28 deubiquitinase (DUBs) inhibitor (USP25/28 IC50 = 0.62/0.7 nM by Ub-Rh110 assay) th at induces HCT116 cellular c-Myc degradation (20-100 μM for 3h or 60 μM for 0.3-3h). AZ1 exhibits antiproliferation activity in cancer cultures (IC50 ≤20 μM; HCT116, HT29 and SW480) and anti-tumor efficacy in an orthotopic model of lung SCC tumours in mice in vivo (125 mg/kg or 375 mg/kg i.p. once every three days, 6 injections total).

AZ-1 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

AZ-1 Suppliers

China 45 United States 4 Global 49

InvivoChem

Tel: 13549236410
Email: sales@invivochem.cn
Country: China
ProdList: 6753
Advantage: 58

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7787
Advantage: 56

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4571
Advantage: 55

ATK CHEMICAL COMPANY LIMITED

Tel: 021-51619050 13301662590
Fax: +86-21-51619052
Email: mandy@atkchemical.com
Country: China
ProdList: 10196
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 7312
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29764
Advantage: 68

Chuzhou KeMail Chemical Technology Co., Ltd

Tel: 0550-5196001 15000891977
Fax: 0550-5196001
Email: wj520wjxby@126.com
Country: China
ProdList: 1925
Advantage: 55

Henan Alfachem Co.,Ltd.

Tel: 0371-0371-55051623 18137891487
Fax: QQ：2853979817
Email: 2853979817@qq.com
Country: China
ProdList: 9964
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

2165322-94-9, AZ-1Related Search:

USP25 and 28 inhibitor AZ-1

Ethanol, 2-[[[5-bromo-2-[[4-fluoro-3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]amino]-

AZ-1;AZ 1;AZ1

USP25/28 inhibitor AZ1

2-((5-bromo-2-((4-fluoro-3-(trifluoromethyl)benzyl)oxy)benzyl)amino)ethanol

AZ-1

Deubiquitinase,USP-25/28 inhibitor AZ1,USP25/28 inhibitor AZ1,inhibit,AZ 1,Inhibitor,AZ-1,DUBs

2-((5-Bromo-2-((4-fluoro-3-(trifluoromethyl)benzyl)oxy)benzyl)amino)ethan-1-ol

AZ1 USP25/28 inhibitor

USP25/28 inhibitor AZ1, 10 mM in DMSO

2165322-94-9

C17H16BrF4NO2