Besifloxacin

Product Name: Besifloxacin
CAS No.: 1398566-43-2
Chemical Name: Besifloxacin
Synonyms: Besifloxacin hydrochloride >=98% (HPLC)
CBNumber: CB44669856
Molecular Formula: C19H22Cl2FN3O3
Formula Weight: 430.3
MOL File: 1398566-43-2.mol

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Besifloxacin Property

storage temp.: -20°C
solubility: DMSO: 2mg/mL, clear (warmed)
form: powder
color: white to light brown

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1608
Product name: Besifloxacin hydrochloride
Purity: ≥98% (HPLC)
Packaging: 10MG
Price: $96.5
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML1608
Product name: Besifloxacin hydrochloride
Purity: ≥98% (HPLC)
Packaging: 50MG
Price: $372.4
Updated: 2025/07/31

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Besifloxacin Chemical Properties,Usage,Production

Uses

(Rac)-Besifloxacin hydrochloride is the enantiomer of Besifloxacin hydrochloride. Besifloxacin hydrochloride is a broad-spectrum fourth-generation fluoroquinolone antibiotic[1].

Biochem/physiol Actions

Besifloxacin is a broad spectrum fourth-generation fluoroquinolone antibiotic. Besifloxacin is effective against gram positive and negative, aerobic and anerobic bacteria. Fluoroquinolones stabilize DNA strand breaks created by DNA gyrase and topoisomerase IV by binding to the enzyme-DNA complex generating persistent, covalent enzyme–DNA adducts, inhibiting DNA synthesis. Besifloxacin inhibits both DNA gyrase and topoisomerase IV at nearly equal concentrations. It is used clinically primarily in the treatment of bacterial conjunctivitis.

IC 50

Quinolone

References

[1] Zhangting Wang, et al. Determination of enantiomeric impurity in besifloxacin hydrochloride by chiral high-performance liquid chromatography with precolumn derivatization. Chirality. 2012 Jul;24(7):526-31. DOI:10.1002/chir.22042

Besifloxacin Preparation Products And Raw materials

Raw materials

Preparation Products

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Besifloxacin Suppliers

China 6 Global 6

Sigma-Aldrich

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1398566-43-2, BesifloxacinRelated Search:

Besifloxacin hydrochloride >=98% (HPLC)

1398566-43-2