ChemicalBook > CAS DataBase List > Mcl1-IN-3
Mcl1-IN-3
- Product Name
- Mcl1-IN-3
- CAS No.
- 1814891-79-6
- Chemical Name
- Mcl1-IN-3
- Synonyms
- Mcl1-IN-3;Mcl1IN3,Mcl-1-IN-3,Mcl1 IN 3;1-[[4-(4-Chloro-3,5-dimethylphenoxy)phenyl]methyl]-6-(2-furanyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid;1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 1-[[4-(4-chloro-3,5-dimethylphenoxy)phenyl]methyl]-6-(2-furanyl)-3-methyl-
- CBNumber
- CB44672638
- Molecular Formula
- C27H22ClN3O4
- Formula Weight
- 487.93
- MOL File
- 1814891-79-6.mol
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Mcl1-IN-3 Property
- Boiling point:
- 680.6±55.0 °C(Predicted)
- Density
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 0.89±0.30(Predicted)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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Mcl1-IN-3 Chemical Properties,Usage,Production
Uses
Mcl1-IN-3 is an inhibitor of Mcl1 extracted from patent WO2015153959A2, compound example 57; has an IC50 and Ki of 0.67 and 0.13 μM, respectively.
References
[1] Nikolovska-Coleska Z, et al. Pyrazolopyridines as inhibitors of Mcl-1 and and their preparation. WO2015153959A2
Mcl1-IN-3 Preparation Products And Raw materials
Raw materials
Preparation Products
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Mcl1-IN-3 Suppliers
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- 15911056312
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