Remibrutinib

ChemicalBook > CAS DataBase List > Remibrutinib

Product Name: Remibrutinib
CAS No.: 1787294-07-8
Chemical Name: Remibrutinib
Synonyms: LOU064;LOU-064;REMIBRUTINIB;Remibrutinib (LOU064);Btk,Inhibitor,inhibit,Remibrutinib,Bruton tyrosine kinase;N-(3-(6-Amino-5-(2-(N-methylacrylamido)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphenyl)-4-cyclopropyl-2-fluorobenzamide;N-(3-{5-[2-(Acryloyl-methyl-amino)-ethoxy]-6-amino-pyrimidin-4-yl}-5-fluoro-2-methyl-phenyl)-4-cyclopropyl-2-fluoro-benzamide;N-[3-[6-Amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluorobenzamide;Benzamide, N-[3-[6-amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluoro-
CBNumber: CB44675356
Molecular Formula: C27H27F2N5O3
Formula Weight: 507.53
MOL File: 1787294-07-8.mol

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Remibrutinib Property

Boiling point:: 634.8±55.0 °C(Predicted)
Density: 1.332±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 125 mg/mL (246.29 mM)
form: Solid
pka: 11.67±0.70(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0103905
Product name: Remibrutinib
Purity: 99.26%
Packaging: 5mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0103905
Product name: Remibrutinib
Purity: 99.26%
Packaging: 10mg
Price: $550
Updated: 2021/12/16

ChemScene

Product number: CS-0103905
Product name: Remibrutinib
Purity: 99.26%
Packaging: 50mg
Price: $1650
Updated: 2021/12/16

ChemScene

Product number: CS-0103905
Product name: Remibrutinib
Purity: 99.26%
Packaging: 100mg
Price: $2250
Updated: 2021/12/16

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Remibrutinib Chemical Properties,Usage,Production

Description

Remibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC₅₀ value of 1 nM. Remibrutinib inhibits BTK activity with an IC₅₀value of 0.023 μM in blood. Remibrutinib has the potential for Chronic urticaria (CU) treatment.

Chemical Properties

White to off-white Solid

Remibrutinib Preparation Products And Raw materials

Raw materials

Preparation Products

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1787294-07-8, RemibrutinibRelated Search:

LOU064

LOU-064

REMIBRUTINIB

N-(3-{5-[2-(Acryloyl-methyl-amino)-ethoxy]-6-amino-pyrimidin-4-yl}-5-fluoro-2-methyl-phenyl)-4-cyclopropyl-2-fluoro-benzamide

Benzamide, N-[3-[6-amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluoro-

Remibrutinib (LOU064)

N-(3-(6-Amino-5-(2-(N-methylacrylamido)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphenyl)-4-cyclopropyl-2-fluorobenzamide

Btk,Inhibitor,inhibit,Remibrutinib,Bruton tyrosine kinase

N-[3-[6-Amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluorobenzamide

1787294-07-8

C27H27F2N5O3