ChemicalBook > CAS DataBase List > PG 931
PG 931
- Product Name
- PG 931
- CAS No.
- 667430-81-1
- Chemical Name
- PG 931
- Synonyms
- PG 931;Ac-Nle-cyclo（Asp-Pro-D-Phe-Arg-Trp-Lys)-Pro-Val-NH2;L-Valinamide, N-acetyl-L-norleucyl-L-α-aspartyl-L-prolyl-D-phenylalanyl-L-arginyl-L-tryptophyl-L-lysyl-L-prolyl-, (2→7)-lactam
- CBNumber
- CB44727460
- Molecular Formula
- C59H85N15O11
- Formula Weight
- 1180.42
- MOL File
- 667430-81-1.mol
More
Less
PG 931 Property
- Density
- 1.41±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble to 2 mg/ml in 25% ethanol / water
- form
- Powder
- pka
- 13.14±0.70(Predicted)
- color
- White to off-white
More
Less
N-Bromosuccinimide Price
Tocris
- Product number
- 5094
- Product name
- PG931
- Packaging
- 1
- Price
- $281
- Updated
- 2021/12/16
Usbiological
- Product number
- 256225
- Product name
- PG 931
- Packaging
- 1mg
- Price
- $602
- Updated
- 2021/12/16
More
Less
PG 931 Chemical Properties,Usage,Production
Biological Activity
PG-931 is an analog of SHU 9119 (HY-P0227). PG-931 is a potent melanocortin 4 (MC4) receptor (IC50=0.58 nM) agonist, more selective than hMC3R (IC50=55 nM) or hMC5R (IC50=2.4 nM). It can reverse hemorrhagic shock and prevent multiple organ damage in vivo in animal experimental models.
in vivo
PG-931 (intravenous injection; 13-10 8 nmol/kg; single dose) produces a dose-dependent restoration of cardiovascular and respiratory functions, and improved survival in Wistar rats with haemorrhagic shock.
| Animal Model: | Wistar rats |
| Dosage: | 13-10 8 nmol/kg |
| Administration: | Intravenous injection; single dose |
| Result: | Exhibitd an anti-shock effect occurred at nanomolar doses. |
target
IC50: 0.58 nM (melanocortin 4 receptor)IC50: 2.4 nM (melanocortin 5 receptor)IC50: 55 nM (melanocortin 3 receptor)
PG 931 Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
PG 931 Suppliers
- Tel
- +86-17380623303 +86-17380623303
- Fax
- 028-62328193
- Caroline@youngshechem.com
- Country
- China
- ProdList
- 4840
- Advantage
- 58
- Tel
- 0571-87213919
- Fax
- 0571-87213919
- Eric@peptidego.com
- Country
- China
- ProdList
- 6756
- Advantage
- 58
- Tel
- +1-2135480471 +1-2135480471
- sales@sarms4muscle.com
- Country
- China
- ProdList
- 10473
- Advantage
- 58
- Tel
- 0571-88211921 13355716090
- Sales@gotopbio.com
- Country
- China
- ProdList
- 2859
- Advantage
- 58
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 29774
- Advantage
- 58
- Tel
- 0571-88211921 15572296305
- sales4@gotopbio.com
- Country
- China
- ProdList
- 5128
- Advantage
- 58
- Tel
- 0571-87213919 17306812703
- 3007955328@qq.com
- Country
- China
- ProdList
- 6445
- Advantage
- 58
- Tel
- 0571-85350119 15888826472
- 15888826472@163.com
- Country
- China
- ProdList
- 2729
- Advantage
- 58
- Tel
- 19961912513
- sales@hongtide.com
- Country
- China
- ProdList
- 4597
- Advantage
- 58
- Tel
- 18014456767
- wenxi@jszkhy.com
- Country
- China
- ProdList
- 1350
- Advantage
- 58