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CANDESARTAN-D4

Product Name
CANDESARTAN-D4
CAS No.
1346604-70-3
Chemical Name
CANDESARTAN-D4
Synonyms
CV-11974-d4;CANDESARTAN-D4;[2H4]-Candesartan;Candesartan M1-d4;Candesartan D4 (CV-11974 D4);2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1-(phenyl-d4)-1'-phenyl]-4-yl]Methyl]-1H-benziMidazole-7-carboxylic Acid;1-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl-2,3,5,6-d4)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid;2-ethoxy-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)(2,3,5,6-2H?)-[1,1'-biphenyl]-4-yl]methyl}-1H-1,3-benzodiazole-7-carboxylic acid;Candesartan D4Q: What is Candesartan D4 Q: What is the CAS Number of Candesartan D4 Q: What is the storage condition of Candesartan D4
CBNumber
CB4477701
Molecular Formula
C24H16D4N6O3
Formula Weight
444.48
MOL File
Mol file
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CANDESARTAN-D4 Property

Melting point:
151-157°C
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
25419
Product name
Candesartan-d4
Purity
≥99% deuterated forms (d1-d4)
Packaging
1mg
Price
$335
Updated
2024/03/01
Cayman Chemical
Product number
25419
Product name
Candesartan-d4
Purity
≥99% deuterated forms (d1-d4)
Packaging
5mg
Price
$669
Updated
2024/03/01
Usbiological
Product number
005550
Product name
Candesartan-d4
Packaging
1mg
Price
$531
Updated
2021/12/16
TRC
Product number
C175578
Product name
Candesartan-d4
Packaging
25mg
Price
$3630
Updated
2021/12/16
ChemScene
Product number
CS-4129
Product name
CandesartanD4
Purity
98.85%
Packaging
1mg
Price
$216
Updated
2021/12/16
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CANDESARTAN-D4 Chemical Properties,Usage,Production

Description

Candesartan-d4 is intended for use as an internal standard for the quantification of candesartan by GC- or LC-MS. Candesartan is an antagonist of the angiotensin II type 1 (AT1) receptor (Kis = 0.17, 0.12, and 0.12 nM for human AT1, rat AT1A, and rat AT1B recombinant receptors, respectively) and an active metabolite of the prodrug candesartan cilexitil (Item No. 10489). It is selective for AT1 over AT2 receptors (Ki = 26,500 nM for the human recombinant AT2 receptor). It inhibits angiotensin II-induced contraction of isolated rabbit aortic strips and increases in blood pressure in rats following intravenous administration (ID50 = 0.033 mg/kg). Formulations containing candesartan have been used in the treatment of hypertension and heart failure.

Chemical Properties

CANDESARTAN-D4 is White to Off-White Solid

Uses

Labelled Candesartan, an angiotensin II type-1 receptor antagonist. Used in treatment of congestive heart failure. Antihypertensive.

Uses

CANDESARTAN-D4 is an angiotensin II type-1 receptor antagonist. Used in treatment of congestive heart failure. Antihypertensive.

CANDESARTAN-D4 Preparation Products And Raw materials

Raw materials

Preparation Products

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CANDESARTAN-D4 Suppliers

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1346604-70-3, CANDESARTAN-D4Related Search:

Octamethylcyclotetrasiloxane Candesartan

  • 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1-(phenyl-d4)-1'-phenyl]-4-yl]Methyl]-1H-benziMidazole-7-carboxylic Acid
  • Candesartan M1-d4
  • CV-11974-d4
  • CANDESARTAN-D4
  • [2H4]-Candesartan
  • Candesartan D4Q: What is Candesartan D4 Q: What is the CAS Number of Candesartan D4 Q: What is the storage condition of Candesartan D4
  • Candesartan D4 (CV-11974 D4)
  • 1-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl-2,3,5,6-d4)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid
  • 2-ethoxy-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)(2,3,5,6-2H?)-[1,1'-biphenyl]-4-yl]methyl}-1H-1,3-benzodiazole-7-carboxylic acid
  • 1346604-70-3
  • C24H16D4N6O3
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