ChemicalBook > CAS DataBase List > (R)-ADX-47273

(R)-ADX-47273

Product Name
(R)-ADX-47273
CAS No.
851881-59-9
Chemical Name
(R)-ADX-47273
Synonyms
(R)-ADX-47273;(R)-ADX-47273, 10 mM in DMSO;Inhibitor,inhibit,mGluR,(R)ADX47273,(R) ADX 47273,Metabotropic glutamate receptors;(4-Fluorophenyl)[(3R)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]methanone;Methanone, (4-fluorophenyl)[(3R)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-
CBNumber
CB44797012
Molecular Formula
C20H17F2N3O2
Formula Weight
369.36
MOL File
851881-59-9.mol
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(R)-ADX-47273 Property

storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0047681
Product name
(R)-ADX-47273
Purity
99.25%
Packaging
5mg
Price
$140
Updated
2021/12/16
Biosynth Carbosynth
Product number
BA166488
Product name
(R)-ADX 47273
Packaging
10mg
Price
$145
Updated
2021/12/16
ChemScene
Product number
CS-0047681
Product name
(R)-ADX-47273
Purity
99.25%
Packaging
10mg
Price
$240
Updated
2021/12/16
AK Scientific
Product number
6718CS
Product name
(4-Fluorophenyl)-[(3R)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl]methanone
Packaging
10mg
Price
$245
Updated
2021/12/16
Biosynth Carbosynth
Product number
BA166488
Product name
(R)-ADX 47273
Packaging
50mg
Price
$507.5
Updated
2021/12/16
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(R)-ADX-47273 Chemical Properties,Usage,Production

Description

(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation . mGluR5|168 nM (EC50)

(R)-ADX-47273 (ADX-47273 (5)) is a potent mGluR5 positive allosteric modulator with an EC50 for potentiation of 168 nM and a 9-fold shift of the glutamate response curve at 1 μM[1].

Uses

(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation .

IC 50

mGlu5: 168 nM (EC50)

References

[1]. Engers DW, et al. Synthesis, SAR and unanticipated pharmacological profiles of analogues of the mGluR5 ago-potentiator ADX-47273. ChemMedChem. 2009 Apr;4(4):505-11.

(R)-ADX-47273 Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-ADX-47273 Suppliers

China 18 United Kingdom 1 United States 3 Global 22
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851881-59-9, (R)-ADX-47273Related Search:


  • (R)-ADX-47273
  • (4-Fluorophenyl)[(3R)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]methanone
  • Methanone, (4-fluorophenyl)[(3R)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-
  • Inhibitor,inhibit,mGluR,(R)ADX47273,(R) ADX 47273,Metabotropic glutamate receptors
  • (R)-ADX-47273, 10 mM in DMSO
  • 851881-59-9