PAT-1251

Product Name: PAT-1251
CAS No.: 2007885-39-2
Chemical Name: PAT-1251
Synonyms: PAT 1251,PAT1251;Lenumlostat (PAT-1251);PAT-1251, 10 mM in DMSO;rel-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)((3R,4R)-3-fluoro-4-hydroxypyrrolidin-1-yl)methanone;Methanone, [3-[[4-(aminomethyl)-6-(trifluoromethyl)-2-pyridinyl]oxy]phenyl][(3R,4R)-3-fluoro-4-hydroxy-1-pyrrolidinyl]-, rel-
CBNumber: CB44797092
Molecular Formula: C18H17F4N3O3
Formula Weight: 399.34
MOL File: 2007885-39-2.mol

More

Less

PAT-1251 Property

Boiling point:: 540.7±50.0 °C(Predicted)
Density: 1.48±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 130 mg/mL (325.54 mM)
form: Solid
pka: 13.23±0.40(Predicted)
color: Light yellow to yellow

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-0028450
Product name: PAT-1251
Purity: 98.17%
Packaging: 5mg
Price: $650
Updated: 2021/12/16

ChemScene

Product number: CS-0028450
Product name: PAT-1251
Purity: 98.17%
Packaging: 10mg
Price: $950
Updated: 2021/12/16

ChemScene

Product number: CS-0028450
Product name: PAT-1251
Purity: 98.17%
Packaging: 25mg
Price: $1950
Updated: 2021/12/16

ChemScene

Product number: CS-0028450
Product name: PAT-1251
Purity: 98.17%
Packaging: 50mg
Price: $2950
Updated: 2021/12/16

ChemScene

Product number: CS-0028450
Product name: PAT-1251
Purity: 98.17%
Packaging: 100mg
Price: $4500
Updated: 2021/12/16

More

Less

PAT-1251 Chemical Properties,Usage,Production

Uses

PAT-1251 is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16 μM, respectively); PAT-1251 is used in the research of fibrotic diseases[1].

References

[1] Rowbottom MW, et al. Identification of 4-(Aminomethyl)-6-(trifluoromethyl)-2-(phenoxy)pyridine Derivatives as Potent, Selective, and Orally Efficacious Inhibitors of the Copper-Dependent Amine Oxidase, Lysyl Oxidase-Like 2 (LOXL2). J Med Chem. 2017 May 25;60(10):4403-4423. DOI:10.1021/acs.jmedchem.7b00345

PAT-1251 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

PAT-1251 Suppliers

China 17 United States 3 Global 20

Chengdu Novel Biomedical Co., Ltd.

Tel: 028-85255396 18302801538
Fax: 028-85255396
Email: cdnovell@163.com
Country: China
ProdList: 2390
Advantage: 58

Chengdu Saint - Kay Biotechnology Co., Ltd.

Tel: 028-85157043 15882256948
Email: 676046971@qq.com
Country: China
ProdList: 4181
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Guangzhou Younan Technology Co., Ltd

Tel: 020-82000279 18988941452
Fax: QQ：3283937693
Email: YN_research@163.com
Country: China
ProdList: 3011
Advantage: 58

Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
ProdList: 5132
Advantage: 58

Kaifeng Mingren Pharmaceutical Co.,LTD

Tel: 0371-65741762
Fax: QQ：2860768577
Email: sales@hasunny.com
Country: China
ProdList: 2380
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
Advantage: 58

RD International Technology Co., Limited

Tel: 18024082417
Email: market@ubiochem.com
Country: China
ProdList: 9835
Advantage: 58

Anhui JYHX CO., LTD.

Tel: 0551-68788198 13295518198
Email: wangyanan@ahjyhx.com
Country: China
ProdList: 1759
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 028-81700200 13308200041
Email: 2851167782@qq.com
Country: China
ProdList: 11146
Advantage: 58

Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
ProdList: 6710
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Adooq Bioscience LLC

Tel: 400-025-6535
Email: sales@adooq.cn
Country: China
ProdList: 6215
Advantage: 58

Absin Bioscience Inc.

Tel: --
Fax: --
Email: chenjw@absin.cn
Country: CHINA
ProdList: 6208
Advantage: 58

Proteintech China

Tel: --
Fax: --
Email: Proteintech-CN@ptglab.com
Country: CHINA
ProdList: 6290
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

2007885-39-2, PAT-1251Related Search:

Methanone, [3-[[4-(aminomethyl)-6-(trifluoromethyl)-2-pyridinyl]oxy]phenyl][(3R,4R)-3-fluoro-4-hydroxy-1-pyrrolidinyl]-, rel-

PAT 1251,PAT1251

rel-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)((3R,4R)-3-fluoro-4-hydroxypyrrolidin-1-yl)methanone

PAT-1251, 10 mM in DMSO

Lenumlostat (PAT-1251)

2007885-39-2