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4-Hydroxy 4-Dedimethylamino Afatinib

Product Name
4-Hydroxy 4-Dedimethylamino Afatinib
CAS No.
2121530-37-6
Chemical Name
4-Hydroxy 4-Dedimethylamino Afatinib
Synonyms
Lansoprazole Impurity 73;Afatinib 4-Hydroxy Analog;1,3-dimethyl-52-nitrosourea;Afatinib Maleate Acid Impurity 3;4-Hydroxy 4-Dedimethylamino Afatinib;2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-hydroxy-, (2E)-;(2E)?-N-?[4-?[(3-?chloro-?4-?fluorophenyl)?amino]?-?7-?[[(3S)?-?tetrahydro-?3-?furanyl]?oxy]?-?6-?quinazolinyl]?-?4-?hydroxy-2-?butenamide;Afatinib impurity 2/4-Hydroxy 4-Dedimethylamino Afatinib/(2E)-N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-hydroxy-2-butenamide
CBNumber
CB44806714
Molecular Formula
C22H20ClFN4O4
Formula Weight
458.87
MOL File
2121530-37-6.mol
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4-Hydroxy 4-Dedimethylamino Afatinib Property

Boiling point:
714.713±60.00 °C(Press: 760.00 Torr)(predicted)
Density 
1.484±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka
11.521±0.43(predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
C376205
Product name
(2E)​-N-​[4-​[(3-​chloro-​4-​fluorophenyl)​amino]​-​7-​[[(3S)​-​tetrahydro-​3-​furanyl]​oxy]​-​6-​quinazolinyl]​-​4-​hydroxy-2-​butenamide
Packaging
25mg
Price
$690
Updated
2021/12/16
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4-Hydroxy 4-Dedimethylamino Afatinib Chemical Properties,Usage,Production

Uses

(2E)?-N-?[4-?[(3-?chloro-?4-?fluorophenyl)?amino]?-?7-?[[(3S)?-?tetrahydro-?3-?furanyl]?oxy]?-?6-?quinazolinyl]?-?4-?hydroxy-2-?butenamide is an impurity of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

4-Hydroxy 4-Dedimethylamino Afatinib Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Hydroxy 4-Dedimethylamino Afatinib Suppliers

Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-66023220 0086-15250997978
Fax
025-58362220
Email
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China
ProdList
7892
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55
Shanghai CR Corporation Limited
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021-80270511; 4006653949
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QQ: 2136646215
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fred.wen@crcorporation.cn
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China
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10044
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CR Corporation Limited
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+8613062833949
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China
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Guangzhou Dreampharm Biotechnology Co., Ltd.
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2710913286@.com
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SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD
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0755-0755-0755-83725350 13380397412
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Hubei Xinyang Medical Technology Co., Ltd
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Guangzhou Juntang Technology Co., Ltd
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Foshan Treasure Biotechnology Co., Ltd
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NANJING WEDO PHARMATECH CO.,LTD.
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Scinova Biotech(Guangzhou) Co., Ltd.
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Shanghai YuZn Pharm. Technology Co.,Ltd.
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HX Pharmaceutical technology co., LTD
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Nanjing Huanuo Biomedical Technology Co., Ltd
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Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd
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Guangzhou Zhenlin Pharmaceutical Technology Co., Ltd
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Nantong Hanfang Biotechnology Co. , Ltd.
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Hubei Moco Chemical Co., Ltd.
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Hubei Ruinuo Pharmaceutical Technology Co., Ltd
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Moxin Chemicals
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+8617320513646
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China National Standard Pharmaceutical Corporation Limited
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Country
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View Lastest Price from 4-Hydroxy 4-Dedimethylamino Afatinib manufacturers

Moxin Chemicals
Product
Afatinib Impurity 2121530-37-6
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
98
Supply Ability
10000
Release date
2025-02-05

2121530-37-6, 4-Hydroxy 4-Dedimethylamino AfatinibRelated Search:


  • 4-Hydroxy 4-Dedimethylamino Afatinib
  • Afatinib impurity 2/4-Hydroxy 4-Dedimethylamino Afatinib/(2E)-N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-hydroxy-2-butenamide
  • Afatinib 4-Hydroxy Analog
  • Afatinib Maleate Acid Impurity 3
  • 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-hydroxy-, (2E)-
  • (2E)?-N-?[4-?[(3-?chloro-?4-?fluorophenyl)?amino]?-?7-?[[(3S)?-?tetrahydro-?3-?furanyl]?oxy]?-?6-?quinazolinyl]?-?4-?hydroxy-2-?butenamide
  • 1,3-dimethyl-52-nitrosourea
  • Lansoprazole Impurity 73
  • 2121530-37-6