4-Hydroxy 4-Dedimethylamino Afatinib

Product Name: 4-Hydroxy 4-Dedimethylamino Afatinib
CAS No.: 2121530-37-6
Chemical Name: 4-Hydroxy 4-Dedimethylamino Afatinib
Synonyms: Lansoprazole Impurity 73;Afatinib 4-Hydroxy Analog;1,3-dimethyl-52-nitrosourea;Afatinib Maleate Acid Impurity 3;4-Hydroxy 4-Dedimethylamino Afatinib;2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-hydroxy-, (2E)-;(2E)?-N-?[4-?[(3-?chloro-?4-?fluorophenyl)?amino]?-?7-?[[(3S)?-?tetrahydro-?3-?furanyl]?oxy]?-?6-?quinazolinyl]?-?4-?hydroxy-2-?butenamide;Afatinib impurity 2/4-Hydroxy 4-Dedimethylamino Afatinib/(2E)-N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-hydroxy-2-butenamide
CBNumber: CB44806714
Molecular Formula: C22H20ClFN4O4
Formula Weight: 458.87
MOL File: 2121530-37-6.mol

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4-Hydroxy 4-Dedimethylamino Afatinib Property

Boiling point:: 714.713±60.00 °C(Press: 760.00 Torr)(predicted)
Density: 1.484±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka: 11.521±0.43(predicted)
InChIKey: XZMUSENASPIMAT-YUKKFKLSSA-N
SMILES: N(C1C=CC(=C(C=1)Cl)F)C1=NC=NC2C=C(C(=CC=21)NC(=O)/C=C/CO)O[C@@H]1COCC1

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: C376205
Product name: (2E)-N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-hydroxy-2-butenamide
Packaging: 25mg
Price: $690
Updated: 2021/12/16

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4-Hydroxy 4-Dedimethylamino Afatinib Chemical Properties,Usage,Production

Uses

(2E)?-N-?[4-?[(3-?chloro-?4-?fluorophenyl)?amino]?-?7-?[[(3S)?-?tetrahydro-?3-?furanyl]?oxy]?-?6-?quinazolinyl]?-?4-?hydroxy-2-?butenamide is an impurity of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

4-Hydroxy 4-Dedimethylamino Afatinib Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-Hydroxy 4-Dedimethylamino Afatinib manufacturers

Moxin Chemicals

Product: Afatinib Impurity 2121530-37-6
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 98
Supply Ability: 10000
Release date: 2025-02-05

2121530-37-6, 4-Hydroxy 4-Dedimethylamino AfatinibRelated Search:

Afatinib Impurity 3 Afatinib Impurity 19 Afatinib Impurity 7 Afatinib IMpurity F R-afatinib Afatinib Afatinib Impurity 10 N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine AfatinibHydrolytic impurity Afatinib Impurity 15 Afatinib Impurity 2 Afatinib Impurity 18 Afatinib Impurity 6 Afatinib IMpurity E Afatinib iMpurity Afatinib Impurity 9 Afatinib Impurity 14 Afatinib Impurity 17

4-Hydroxy 4-Dedimethylamino Afatinib

Afatinib impurity 2/4-Hydroxy 4-Dedimethylamino Afatinib/(2E)-N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-hydroxy-2-butenamide

Afatinib 4-Hydroxy Analog

Afatinib Maleate Acid Impurity 3

2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-hydroxy-, (2E)-

(2E)?-N-?[4-?[(3-?chloro-?4-?fluorophenyl)?amino]?-?7-?[[(3S)?-?tetrahydro-?3-?furanyl]?oxy]?-?6-?quinazolinyl]?-?4-?hydroxy-2-?butenamide

1,3-dimethyl-52-nitrosourea

Lansoprazole Impurity 73

2121530-37-6