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FD-1080

Product Name
FD-1080
CAS No.
1151666-58-8
Chemical Name
FD-1080
Synonyms
FD-1080;FD-1080(Sodium);Heptamethine cyanine dye FD1080;Heptamethine cyanine dye FD-1080;Heptamethine cyanine dye FD 1080;Sodium 4-(2-(2-(2-chloro-3-(2-(1-(4-sulfonatobutyl)benzo[cd]indol-1-ium-2-yl)vinyl)cyclohex-2-en-1-ylidene)ethylidene)benzo[cd]indol-1(2H)-yl)butane-1-sulfonate
CBNumber
CB44819576
Molecular Formula
C40H40ClN2NaO6S2
Formula Weight
767.33
MOL File
1151666-58-8.mol
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FD-1080 Property

form 
Solid
color 
Brown to black
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Hazard and Precautionary Statements (GHS)

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FD-1080 Chemical Properties,Usage,Production

Biological Activity

FD-1080 is a fluorophore with excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm) for in vivo imaging.

in vitro

FD-1080 shows superior photostability under the continuous laser irradiation. The quantum yield of FD-1080 is 0.31%, and can be increased to 5.94% after combining with fetal bovine serum (FBS) to form FD-1080 -FBS complexes.

in vivo

The 1064 nm NIR-II excitation of FD-1080 is demonstrated with the high tissue penetration depth and superior imaging resolution compared to NIR excitation from 650 nm to 980 nm. Deeptissue and high-resolution in vivo imaging for the left hindlimb vasculature, abdomen, and brain vessels were realized, allowing penetration through intact skin, tissue, and skull. It also quantifies the respiratory rate based on the dynamic imaging of respiratory craniocaudal motion of the liver for the awake and anaesthetized mouse.

FD-1080 Preparation Products And Raw materials

Raw materials

Preparation Products

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FD-1080 Suppliers

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