1-(4-(2-((5-(ethoxymethyl)-2-methylphenyl)amino)oxazol-5-yl)phenyl)imidazolidin-2-one

Product Name: 1-(4-(2-((5-(ethoxymethyl)-2-methylphenyl)amino)oxazol-5-yl)phenyl)imidazolidin-2-one
CAS No.: 1974336-09-8
Chemical Name: 1-(4-(2-((5-(ethoxymethyl)-2-methylphenyl)amino)oxazol-5-yl)phenyl)imidazolidin-2-one
Synonyms: 1-[4-[2-[5-(ethoxymethyl)-2-methylanilino]-1,3-oxazol-5-yl]phenyl]imidazolidin-2-one;1-(4-(2-((5-(ethoxymethyl)-2-methylphenyl)amino)oxazol-5-yl)phenyl)imidazolidin-2-one;2-Imidazolidinone, 1-[4-[2-[[5-(ethoxymethyl)-2-methylphenyl]amino]-5-oxazolyl]phenyl]-
CBNumber: CB44868554
Molecular Formula: C22H24N4O3
Formula Weight: 392.45
MOL File: 1974336-09-8.mol

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1-(4-(2-((5-(ethoxymethyl)-2-methylphenyl)amino)oxazol-5-yl)phenyl)imidazolidin-2-one Property

Density: 1.242±0.06 g/cm3(Predicted)
pka: 13.70±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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1-(4-(2-((5-(ethoxymethyl)-2-methylphenyl)amino)oxazol-5-yl)phenyl)imidazolidin-2-one Chemical Properties,Usage,Production

Uses

AB8939 is an effective small moleculeMicrotubule/Tubulin polymerization inhibitor with anti-tumor activity (it inhibits tumor cell proliferation with an IC50 of less than 10 nM). AB8939 can effectively evade resistance mechanisms mediated by things like P-glycoprotein and myeloperoxidase. AB8939 can induce G2/M phase cell cycle arrest and apoptosis in cells[1].

References

[1] Martine Humbert PhD, et al. Anticancer Activity of a Highly Potent Small Molecule Tubulin Polymerization Inhibitor, AB8939. Blood. Volume 134, Supplement 1, 13 November 2019, Page 2075.

1-(4-(2-((5-(ethoxymethyl)-2-methylphenyl)amino)oxazol-5-yl)phenyl)imidazolidin-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(4-(2-((5-(ethoxymethyl)-2-methylphenyl)amino)oxazol-5-yl)phenyl)imidazolidin-2-one Suppliers

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1974336-09-8, 1-(4-(2-((5-(ethoxymethyl)-2-methylphenyl)amino)oxazol-5-yl)phenyl)imidazolidin-2-oneRelated Search:

1-(4-(2-((5-(ethoxymethyl)-2-methylphenyl)amino)oxazol-5-yl)phenyl)imidazolidin-2-one

2-Imidazolidinone, 1-[4-[2-[[5-(ethoxymethyl)-2-methylphenyl]amino]-5-oxazolyl]phenyl]-

1-[4-[2-[5-(ethoxymethyl)-2-methylanilino]-1,3-oxazol-5-yl]phenyl]imidazolidin-2-one

1974336-09-8