ChemicalBook > CAS DataBase List > N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide

N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide

Product Name
N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide
CAS No.
1816989-16-8
Chemical Name
N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide
Synonyms
SY-1365;Mevociclib;Mevociclib，SY-1365;SY-1365;SY 1365;SY1365;N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide;N-[(1S,3R)-3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]-1-methylcyclohexyl]-5-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-2-pyridinecarboxamide;Inhibitor,triple negative breast cancer,TNBC,Mevociclib,Cyclin dependent kinase,SY1365,tumors,cancers,cell,inhibit,solid,CDK,small,SY 1365,CDK7/CycH/MAT1,lung;2-Pyridinecarboxamide, N-[(1S,3R)-3-[[5-chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]-1-methylcyclohexyl]-5-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-
CBNumber
CB44869298
Molecular Formula
C31H35ClN8O2
Formula Weight
587.11
MOL File
1816989-16-8.mol
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N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide Property

Density 
1.34±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 125 mg/mL (212.90 mM)
pka
12.04±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0095954
Product name
Mevociclib
Purity
99.27%
Packaging
5mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-0095954
Product name
Mevociclib
Purity
99.27%
Packaging
10mg
Price
$650
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611907
Product name
SY-1365
Purity
>98%
Packaging
50mg
Price
$1802
Updated
2021/12/16
ChemScene
Product number
CS-0095954
Product name
Mevociclib
Purity
99.27%
Packaging
50mg
Price
$2000
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611907
Product name
SY-1365
Purity
>98%
Packaging
100mg
Price
$2839
Updated
2021/12/16
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N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide Chemical Properties,Usage,Production

Uses

N-[(1S,3R)-3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]-1-methylcyclohexyl]-5-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-2-pyridinecarboxamide is a CDK7 inhibitor and is used for anticancer treatments.

N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide Suppliers

China 21 United States 3 Global 24
ShangHai Caerulum Pharma Discovery Co., Ltd.
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18149758185
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sales-cpd@caerulumpharma.com
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China
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3423
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Shanghai YuanQi Biotechnology Co., Ltd.
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+86-2332782371 +86-18120098618
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sales@adobechem.com
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China
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1250
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50
Shanghai SuperLan Chemcial Technique Centre
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021-2022843681 15618226720
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+86-21-51601218
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chaolaichem@foxmail.com
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China
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9038
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Amadis Chemical Company Limited
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571-89925085
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0086-571-89925065
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sales@amadischem.com
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China
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DC Chemicals
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021-58447131 13564518121
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sales@dcchemicals.com
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China
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Changzhou Chenhong Biotechnology Co., Ltd.
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0519-85788828 13775037613
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sales@chemrenpharm.com
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China
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3553
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767
Fax
QQ 3610331285
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sales@chemegen.com
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China
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11289
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Taizhou Nanfeng Pharmaceutical Research Institute
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12345678910
Fax
nanfengdrug@163
Email
nanfengdrug@163.com
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China
ProdList
15323
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Chunchuang (Wuhan) Technology Co., Ltd
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15342225168
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yutianchun2007@126.com
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China
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10006
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cjbscvictory
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13348960310 13348960310
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3003867561@qq.com
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Hubei Guangao Biotechnology Co., Ltd
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027-027-59223056 18162699093
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027-59223056
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1208480011@qq.com
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Hubei xingongli Chemical Co., Ltd
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027-59106151 15172325309
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027-59503710
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1400858877@qq.com
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China
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9965
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Zhengzhou convergence chemical co., LTD
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0371-0371-55153829 18003835034
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18003835034（微信）
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2853979819@qq.com
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China
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InvivoChem
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13549236410
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sales@invivochem.cn
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China
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TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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China
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Hubei Chenghai Chemical Co., Ltd
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18327245847 18327245847
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1400838877@qq.com
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China
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Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
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021-59167510 18117107507
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vip@med-life.cn
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China
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Nanjing Shizhou Biology Technology Co.,Ltd
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025-85560043 15850508050
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025-85563444
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cindy.huang@synzest.com
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China
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RD International Technology Co., Limited
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18024082417
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market@ubiochem.com
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China
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9180
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ATK CHEMICAL COMPANY LIMITED
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+undefined-21-51877795
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+86 21 5161 9052/ 5187 7796
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ivan@atkchemical.com
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China
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32686
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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1816989-16-8, N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamideRelated Search:


  • N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide
  • SY-1365
  • SY-1365;SY 1365;SY1365
  • 2-Pyridinecarboxamide, N-[(1S,3R)-3-[[5-chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]-1-methylcyclohexyl]-5-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-
  • N-[(1S,3R)-3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]-1-methylcyclohexyl]-5-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-2-pyridinecarboxamide
  • Mevociclib
  • Mevociclib，SY-1365
  • Inhibitor,triple negative breast cancer,TNBC,Mevociclib,Cyclin dependent kinase,SY1365,tumors,cancers,cell,inhibit,solid,CDK,small,SY 1365,CDK7/CycH/MAT1,lung
  • 1816989-16-8
  • C31H35ClN8O2