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MONOBEHENIN

Product Name
MONOBEHENIN
CAS No.
30233-64-8
Chemical Name
MONOBEHENIN
Synonyms
MONOBEHENIN;1-MONOBEHENIN;KeMester 6500;MONODOCOSANOIN;Glycetyl Behenate;Glyceryl monobehenate;Docosanoin, Mono- (7CI);Monostearin Impurity 37;Behenic acid monoglyceride;n-Docosanoicacidglycerolester
CBNumber
CB4489612
Molecular Formula
C25H50O4
Formula Weight
414.66
MOL File
30233-64-8.mol
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MONOBEHENIN Property

Density 
0.93[at 20℃]
vapor pressure 
0.001Pa at 25℃
solubility 
Soluble, when heated, in chloroform and dichloromethane and in many organic solvents; slightly soluble in hot ethanol (96%); practically insoluble in cold ethanol (95%), hexane, mineral oil, and water.
form 
A solid
color 
White to off-white
Water Solubility 
100ng/L at 25℃
LogP
8.58 at 25℃
EPA Substance Registry System
Docosanoic acid, monoester with 1,2,3-propanetriol (30233-64-8)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-B0798
Product name
Monobehenin
Packaging
100mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-B0798
Product name
Monobehenin
Packaging
500mg
Price
$450
Updated
2021/12/16
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MONOBEHENIN Chemical Properties,Usage,Production

Chemical Properties

Glyceryl behenate occurs as a fine white-yellow powder, as a hard waxy mass or pellet, or as white or almost white unctuous flakes. It has a faint odor.

Production Methods

Glyceryl behenate is prepared by the esterification of glycerin by behenic acid (C22 fatty acid) without the use of catalysts. In the case of Compritol 888 ATO (Gattefosse′), raw materials used are of vegetable origin, and the esterified material is atomized by spraycooling.

Definition

ChEBI: 1-behenoylglycerol is a fatty acid ester resulting from the formal condensation of the hydroxy group at position-1 of glycerol with the carboxy group of docosanoic acid. It has a role as a plant metabolite and an antineoplastic agent. It is a 1-monoglyceride and a fatty acid ester. It is functionally related to a glycerol and a docosanoic acid.

Pharmaceutical Applications

Glyceryl behenate is used in cosmetics, foods, and oral pharmaceutical formulations.
In pharmaceutical formulations, glyceryl behenate is mainly used as a lubricant in the preparation of oral tablets and capsules. It has good binding properties, it does not affect tablet hardness and is unaffected by mixing or production parameters. Glyceryl behenate has been investigated for the encapsulation of various drugs such as retinoids. It has also been investigated for use in the preparation of sustained-release tablets; as a matrix-forming agent for the controlled release of water-soluble drugs; and it can also be used as a hot-melt coating agent sprayed onto a powder or drug-loaded sugar beads and granules. It may also be incorporated via extrusion/spheronization into pellets, which can be further compressed into tablets.
Glyceryl behenate is used in oral enteric-coated pellets, powders and suspensions. It is also used in controlled, extended-release and orally disintegrating tablets. For oral preparations, glyceryl behenate forms a lipidic matrix for sustained-release formulations. It has been used along with acid-soluble or swellable polymers to mask the bitter or unpleasant taste of the medicament with improved palatability.
Glyceryl behenate has been used for the preparation of ophthalmic inserts.
In cosmetics, glyceryl behenate is used as a skin conditioning agent, emollient and viscosity-increasing agent in emulsions. It also improves the heat stability of emulsions and is a gelifying agent for various oils. For topical formulations, it is used as a thickening agent for oily phases. It is also used as a surfactant or emulsifying agent.

Safety

Glyceryl behenate is used in cosmetics, foods and oral pharmaceutical formulations, and is generally regarded as a relatively nonirritant and nontoxic material. The US Cosmetic Ingredients Review Expert Panel evaluated glyceryl behenate and concluded that it is safe for use in cosmetic formulations in present practices of use and concentration.
LD50 (mouse, oral): 5 g/kg

storage

Glyceryl behenate should be stored in a tightly closed container, at a temperature less than 35°C.

Regulatory Status

GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral capsules, tablets, and suspensions). Included in the Canadian List of Acceptable Non-medicinal Ingredients.

MONOBEHENIN Preparation Products And Raw materials

Raw materials

Preparation Products

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MONOBEHENIN Suppliers

Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2866
Advantage
58
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
5047
Advantage
50
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Yichang Zhongyitai Trading Co., Ltd.
Tel
0717-6449896 13886658719
Fax
0717-6558598
Email
root@zhongyitai.com
Country
China
ProdList
1977
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18070
Advantage
56
Mashilabs (Shanghai) Co.,Ltd.
Tel
19916721580
Fax
QQ:3154870176
Email
mafarm@126.com
Country
China
ProdList
4301
Advantage
58
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9906
Advantage
50
Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
ProdList
9171
Advantage
60
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View Lastest Price from MONOBEHENIN manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Glyceryl Behenate 30233-64-8
Price
US $120.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-24
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Monobehenin 30233-64-8
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-03
Shaanxi Dideu Medichem Co. Ltd
Product
MONOBEHENIN 30233-64-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-07-18

30233-64-8, MONOBEHENINRelated Search:


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