ELA-11 (human)

Product Name: ELA-11 (human)
CAS No.: 1784687-32-6
Chemical Name: ELA-11 (human)
Synonyms: ELA-11 (human);L-Proline, L-cysteinyl-L-methionyl-L-prolyl-L-leucyl-L-histidyl-L-seryl-L-arginyl-L-valyl-L-prolyl-L-phenylalanyl-
CBNumber: CB44902715
Molecular Formula: C58H90N16O13S2
Formula Weight: 1283.56
MOL File: 1784687-32-6.mol

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ELA-11 (human) Property

Density: 1.47±0.1 g/cm3(Predicted)
form: Solid
pka: 3.43±0.20(Predicted)
color: White to off-white
Sequence: Cys-Met-Pro-Leu-His-Ser-Arg-Val-Pro-Phe-Pro

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Hazard and Precautionary Statements (GHS)

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ELA-11 (human) Chemical Properties,Usage,Production

Uses

ELA-11(human), a peptide, is a full agonist of human apelin receptor, with a pKi of 7.85. ELA-11(human) completely inhibits Forskolin-induced cAMP production and stimulates β-arrestin recruitment[1].

References

[1] Yang P, et, al. Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension. Circulation. 2017 Mar 21;135(12):1160-1173. DOI:10.1161/CIRCULATIONAHA.116.023218

ELA-11 (human) Preparation Products And Raw materials

Raw materials

Preparation Products

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ELA-11 (human) Suppliers

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1784687-32-6, ELA-11 (human)Related Search:

ELA-11 (human)

L-Proline, L-cysteinyl-L-methionyl-L-prolyl-L-leucyl-L-histidyl-L-seryl-L-arginyl-L-valyl-L-prolyl-L-phenylalanyl-

1784687-32-6