(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3-methoxypropanoic acid

Product Name: (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3-methoxypropanoic acid
CAS No.: 1569103-64-5
Chemical Name: (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3-methoxypropanoic acid
Synonyms: N-Fmoc-N,O-dimethyl-L-serine;Fmoc-?N,?O-?dimethyl-?L-?serine;L-Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N,O-dimethyl-;(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-methoxypropanoic acid;(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3-methoxypropanoic acid
CBNumber: CB44921426
Molecular Formula: C20H21NO5
Formula Weight: 355.38
MOL File: 1569103-64-5.mol

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(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3-methoxypropanoic acid Property

Boiling point:: 540.6±50.0 °C(Predicted)
Density: 1.266±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
form: Solid
pka: 3.42±0.10(Predicted)
color: White to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Acrotein

Product number: A-8766
Product name: N-Fmoc-N,O-dimethyl-L-serine
Purity: 97%
Packaging: 0.5g
Price: $256.7
Updated: 2021/12/16

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(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3-methoxypropanoic acid Chemical Properties,Usage,Production

Uses

N-Fmoc-N,O-dimethyl-L-serine is a serine derivative that can be used for coibamide A synthesis. Coibamide A is a marine natural product with potent antiproliferative activity against human cancer cells[1][2].

References

[1] Yao G, et al. Efficient Synthesis and Stereochemical Revision of Coibamide A. J Am Chem Soc. 2015 Oct 28;137(42):13488-91. DOI:10.1021/jacs.5b09286
[2] Tranter D, et al. Coibamide A Targets Sec61 to Prevent Biogenesis of Secretory and Membrane Proteins. ACS Chem Biol. 2020 Aug 21;15(8):2125-2136. DOI:10.1021/acschembio.0c00325

(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3-methoxypropanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3-methoxypropanoic acid Suppliers

China 25 United States 1 Global 26

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1569103-64-5, (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3-methoxypropanoic acidRelated Search:

N-（(9H-fluoren-9-ylmethoxy)carbonyl）-N-methyl-O-propyl-L-S (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-propoxypropanoic acid Fmoc-2-Amino-5,5,5-F-N-Me-L-Norvaline N-（(9H-fluoren-9-ylmethoxy)carbonyl）-O-(2-hydroxy-2-methyl (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-hydroxypentanoic acid N-（(9H-fluoren-9-ylmethoxy)carbonyl）-O-(3-methylbutyl)-L-S (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(2-hydroxy-2-methylpropoxy)propanoic acid

(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3-methoxypropanoic acid

N-Fmoc-N,O-dimethyl-L-serine

(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-methoxypropanoic acid

L-Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N,O-dimethyl-

Fmoc-?N,?O-?dimethyl-?L-?serine

1569103-64-5