ChemicalBook > CAS DataBase List > PLB-1001

PLB-1001

Product Name
PLB-1001
CAS No.
1440964-89-5
Chemical Name
PLB-1001
Synonyms
CBT-101;CBI-3103;BOZITINIB;PLB-1001 ;Vebreltinib;PLB-1001 (Bozitinib;BOZITINIB (PLB-1001);Bozitinib (Vebreltinib);Bozitinib, 10 mM in DMSO;CBT101,CBT 101,Vebreltinib,PLB 1001,PLB1001,inhibit,Bozitinib,c-Met/HGFR,Inhibitor
CBNumber
CB44923804
Molecular Formula
C20H15F3N8
Formula Weight
424.38
MOL File
1440964-89-5.mol
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PLB-1001 Property

Density 
1.68±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 50 mg/mL (117.82 mM)
form 
Solid
pka
0.15±0.12(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0088607
Product name
Bozitinib
Purity
99.66%
Packaging
5mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-0088607
Product name
Bozitinib
Purity
99.66%
Packaging
10mg
Price
$550
Updated
2021/12/16
ChemScene
Product number
CS-0088607
Product name
Bozitinib
Purity
99.66%
Packaging
25mg
Price
$1100
Updated
2021/12/16
ChemScene
Product number
CS-0088607
Product name
Bozitinib
Purity
99.66%
Packaging
50mg
Price
$1850
Updated
2021/12/16
ChemScene
Product number
CS-0088607
Product name
Bozitinib
Purity
99.66%
Packaging
100mg
Price
$2750
Updated
2021/12/16
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PLB-1001 Chemical Properties,Usage,Production

Uses

Bozitinib (PLB-1001) is a highly selective c-MET kinase inhibitor with blood-brain barrier permeability. Bozitinib (PLB-1001) is a ATP-competitive small-molecule inhibitor, binds to the conventional ATP-binding pocket of the tyrosine kinase superfamily[1].

References

[1] Hu H, et al. Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor. Cell. 2018 Nov 29;175(6):1665-1678.e18. DOI:10.1016/j.cell.2018.09.038

PLB-1001 Preparation Products And Raw materials

Raw materials

Preparation Products

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PLB-1001 Suppliers

WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
Tel
17702719238 18971495150;
Email
sales@sun-shinechem.com
Country
China
ProdList
1077
Advantage
64
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4769
Advantage
55
Shanghai Beckham Medical Technology Co., Ltd
Tel
13816613772
Fax
QQ: 12922499
Email
huahero21@sina.com
Country
China
ProdList
2391
Advantage
55
Shanghai Qiao Chemical Science Co., Ltd
Tel
021-58892003
Email
info@qiaochem.com
Country
China
ProdList
6059
Advantage
65
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
NanJing Xienuo bio Co.,Ltd.
Tel
025-84112752 13805181430
Fax
+86-25-84846489
Email
154301870@qq.com
Country
China
ProdList
1000
Advantage
55
Kaixin Chemical (Hong Kong) Limited
Tel
010-88886666-01 13112345678
Fax
CDXH21@126.com
Email
loyson@tcypharm.com
Country
China
ProdList
597
Advantage
55
Suzhou Rovathin Foreign Trade Co.,Ltd
Tel
0512-65816829 18662214788
Fax
0512-65816829
Email
info@rovathin.com.cn
Country
China
ProdList
9987
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58

1440964-89-5, PLB-1001 Related Search:


  • PLB-1001
  • BOZITINIB
  • BOZITINIB (PLB-1001)
  • CBT-101
  • 1,2,4-Triazolo[4,3-b]pyridazine, 6-(1-cyclopropyl-1H-pyrazol-4-yl)-3-[difluoro(6-fluoro-2-methyl-2H-indazol-5-yl)methyl]-
  • 6-(1-cyclopropylpyrazol-4-yl)-3-[difluoro-(6-fluoro-2-methylindazol-5-yl)methyl]-[1,2,4]triazolo[4,3-b]pyridazine
  • Vebreltinib
  • 6-(1-cyclopropyl-1H-pyrazol-4-yl)-3-(difluoro(6-fluoro-2-methyl-2H-indazol-5-yl)methyl)-[1,2,4]triazolo[4,3-b]pyridazine
  • CBT101,CBT 101,Vebreltinib,PLB 1001,PLB1001,inhibit,Bozitinib,c-Met/HGFR,Inhibitor
  • 6-(1-cyclopropyl-1H-pyrazolyl)-3- (difluoro(6-fluoro-2-rnelhyl-2H-indazol-5-yl) methy)-[1,2,4]triazolo[4,3-b] pyridazine
  • Bozitinib (Vebreltinib)
  • Bozitinib, 10 mM in DMSO
  • CBI-3103
  • PLB-1001 (Bozitinib
  • 1440964-89-5
  • C20H15F3N8