ChemicalBook > CAS DataBase List > PLB-1001
PLB-1001
- Product Name
- PLB-1001
- CAS No.
- 1440964-89-5
- Chemical Name
- PLB-1001
- Synonyms
- CBT-101;CBI-3103;BOZITINIB;PLB-1001 ;Vebreltinib;PLB-1001 (Bozitinib;BOZITINIB (PLB-1001);Bozitinib (Vebreltinib);Bozitinib, 10 mM in DMSO;CBT101,CBT 101,Vebreltinib,PLB 1001,PLB1001,inhibit,Bozitinib,c-Met/HGFR,Inhibitor
- CBNumber
- CB44923804
- Molecular Formula
- C20H15F3N8
- Formula Weight
- 424.38
- MOL File
- 1440964-89-5.mol
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PLB-1001 Property
- Density
- 1.68±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 50 mg/mL (117.82 mM)
- form
- Solid
- pka
- 0.15±0.12(Predicted)
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0088607
- Product name
- Bozitinib
- Purity
- 99.66%
- Packaging
- 5mg
- Price
- $350
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0088607
- Product name
- Bozitinib
- Purity
- 99.66%
- Packaging
- 10mg
- Price
- $550
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0088607
- Product name
- Bozitinib
- Purity
- 99.66%
- Packaging
- 25mg
- Price
- $1100
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0088607
- Product name
- Bozitinib
- Purity
- 99.66%
- Packaging
- 50mg
- Price
- $1850
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0088607
- Product name
- Bozitinib
- Purity
- 99.66%
- Packaging
- 100mg
- Price
- $2750
- Updated
- 2021/12/16
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PLB-1001 Chemical Properties,Usage,Production
Uses
Bozitinib (PLB-1001) is a highly selective c-MET kinase inhibitor with blood-brain barrier permeability. Bozitinib (PLB-1001) is a ATP-competitive small-molecule inhibitor, binds to the conventional ATP-binding pocket of the tyrosine kinase superfamily[1].
References
[1] Hu H, et al. Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor. Cell. 2018 Nov 29;175(6):1665-1678.e18. DOI:10.1016/j.cell.2018.09.038
PLB-1001 Preparation Products And Raw materials
Raw materials
Preparation Products
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PLB-1001 Suppliers
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- Country
- China
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