ChemicalBook > CAS DataBase List > IGF-I (24-41)

IGF-I (24-41)

Product Name
IGF-I (24-41)
CAS No.
135861-49-3
Chemical Name
IGF-I (24-41)
Synonyms
IGF-I (24-41);YFNKPTGYGSSSRRAPQT;IGF-I FRAG 24-41 HUMAN;INSULIN-LIKE GROWTH FACTOR I (24-41);INSULIN-LIKE GROWTH FACTOR I FRAGMENT 24-41, HUMAN;TYR-PHE-ASN-LYS-PRO-THR-GLY-TYR-GLY-SER-SER-SER-ARG-ARG-ALA-PRO-GLN-THR;H-TYR-PHE-ASN-LYS-PRO-THR-GLY-TYR-GLY-SER-SER-SER-ARG-ARG-ALA-PRO-GLN-THR-;H-TYR-PHE-ASN-LYS-PRO-THR-GLY-TYR-GLY-SER-SER-SER-ARG-ARG-ALA-PRO-GLN-THR-OH;H2N-TYR-PHE-ASN-LYS-PRO-THR-GLY-TYR-GLY-SER-SER-SER-ARG-ARG-ALA-PRO-GLN-THR-OH;L-Threonine, L-tyrosyl-L-phenylalanyl-L-asparaginyl-L-lysyl-L-prolyl-L-threonylglycyl-L-tyrosylglycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-
CBNumber
CB4493158
Molecular Formula
C88H133N27O28
Formula Weight
2017.16
MOL File
135861-49-3.mol
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IGF-I (24-41) Property

Density 
1.56±0.1 g/cm3(Predicted)
storage temp. 
-15°C
form 
Solid
color 
White to off-white
Sequence
Tyr-Phe-Asn-Lys-Pro-Thr-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biorbyt Ltd
Product number
orb372431
Product name
IGF-I (24-41)
Purity
> 95%
Packaging
1mg
Price
$419.9
Updated
2021/12/16
Biorbyt Ltd
Product number
orb372431
Product name
IGF-I (24-41)
Purity
> 95%
Packaging
5mg
Price
$885.7
Updated
2021/12/16
Biorbyt Ltd
Product number
orb372431
Product name
IGF-I (24-41)
Purity
> 95%
Packaging
10mg
Price
$1322.6
Updated
2021/12/16
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IGF-I (24-41) Chemical Properties,Usage,Production

Uses

IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) is amino acids 24 to 41 fragment of IGF-I. IGF-I, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I is partly responsible for systemic growth hormone (GH) activities. IGF-I has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) regulates somatic growth and behavioral development[1][2][3].

in vivo

IGF-I (24-41) (ICV; 200 ng dose; 2 μL; postnatal days 2, 4, and 7) regulates somatic growth and behavioral development[2].

Animal Model:Mice of an outbred Swiss-derived strain (CD-l) weighing 30-33g (virgin males) or 28-30g (nulliparous females)[2]
Dosage:200 ng dose; 2 μL
Administration:ICV; postnatal days (PND) 2, 4, and 7
Result:Increased the rate of ultrasonic calls of the pups measured on PND8.

References

[1] Puche JE, et al. Human conditions of insulin-like growth factor-I (IGF-I) deficiency. J Transl Med. 2012 Nov 14;10:224. DOI:10.1186/1479-5876-10-224
[2] D Santucci, et al. IGF-I and IGF-I24-41 but not IGF-I57-70 affect somatic and neurobehavioral development of newborn male mice. Brain Res Bull. 1994;35(4):367-71. DOI:10.1016/0361-9230(94)90115-5
[3] Dan Meng, et al. Insulin-like growth factor-I (IGF-I) induces epidermal growth factor receptor transactivation and cell proliferation through reactive oxygen species. Free Radic Biol Med. 2007 Jun 1;42(11):1651-60. DOI:10.1016/j.freeradbiomed.2007.01.037

IGF-I (24-41) Preparation Products And Raw materials

Raw materials

Preparation Products

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IGF-I (24-41) Suppliers

GL Biochem (Shanghai) Ltd
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135861-49-3, IGF-I (24-41)Related Search:


  • INSULIN-LIKE GROWTH FACTOR I FRAGMENT 24-41, HUMAN
  • INSULIN-LIKE GROWTH FACTOR I (24-41)
  • IGF-I FRAG 24-41 HUMAN
  • IGF-I (24-41)
  • H-TYR-PHE-ASN-LYS-PRO-THR-GLY-TYR-GLY-SER-SER-SER-ARG-ARG-ALA-PRO-GLN-THR-
  • H-TYR-PHE-ASN-LYS-PRO-THR-GLY-TYR-GLY-SER-SER-SER-ARG-ARG-ALA-PRO-GLN-THR-OH
  • H2N-TYR-PHE-ASN-LYS-PRO-THR-GLY-TYR-GLY-SER-SER-SER-ARG-ARG-ALA-PRO-GLN-THR-OH
  • TYR-PHE-ASN-LYS-PRO-THR-GLY-TYR-GLY-SER-SER-SER-ARG-ARG-ALA-PRO-GLN-THR
  • L-Threonine, L-tyrosyl-L-phenylalanyl-L-asparaginyl-L-lysyl-L-prolyl-L-threonylglycyl-L-tyrosylglycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-
  • YFNKPTGYGSSSRRAPQT
  • 135861-49-3
  • C88H133N27O28