Pheromonotropin
Description Discovery Regulation of synthesis and release ? Distribution of mRNA Biological functions- Product Name
- Pheromonotropin
- CAS No.
- 141281-40-5
- Chemical Name
- Pheromonotropin
- Synonyms
- pheromonotropin;pheromonotropin, Pseudaletia;L-Leucinamide, L-lysyl-L-leucyl-L-seryl-L-tyrosyl-L-α-aspartyl-L-α-aspartyl-L-lysyl-L-valyl-L-phenylalanyl-L-α-glutamyl-L-asparaginyl-L-valyl-L-α-glutamyl-L-phenylalanyl-L-threonyl-L-prolyl-L-arginyl-
- CBNumber
- CB4498320
- Molecular Formula
- C101H155N25O30
- Formula Weight
- 2199.46
- MOL File
- 141281-40-5.mol
Pheromonotropin Property
- Density
- 1.45±0.1 g/cm3(Predicted)
N-Bromosuccinimide Price
- Product number
- P4070-65
- Product name
- Pheromonotropin
- Packaging
- 1mg
- Price
- $531
- Updated
- 2021/12/16
Pheromonotropin Chemical Properties,Usage,Production
Description
PBAN activates pheromone biosynthesis in lepidopteran sex pheromone glands. MRCH is structurally identical to PBAN. PBAN is a member of the FXPRLamide peptide family and is processed from a precursor peptide encoded by the DH-PBAN gene.
Discovery
PBAN was first discovered as a peptide hormone that is produced by the brain-subesophageal ganglion (Br-SG) complex. It activates the biosynthesis of the sex pheromone in the pheromone glands of the corn earworm, Heliothis/Helicoverpa zea.1 This hormone was isolated from the H. zea Br-SG complexes. Two variants have been isolated in the silkworm Bombyx mori.MRCH was first discovered as the hormone controlling the melanization of the larval cuticle of the armyworm Mythimna separate (Leucania, Pseudaletia) isolated from the head extract of B. mori.
Regulation of synthesis and release
In B. mori, two paired mandibular neuromere (SMx) cells and three paired maxillary neuromere (SMd) cells of the SG are involved in PBAN secretion. The regulation of synthesis and the route of secretion are the same as for DH.
? Distribution of mRNA
In B. mori, PBANR mRNA is detected mainly in the pheromone glands (PGs) immediately after adult emergence and in the developing ovaries. Lower levels of mRNA are detected in the midgut and the brain of 6-day-old fifth instar larvae.
Biological functions
The target of PBAN in adult female moths is the PG cells, which are found as intersegmental tissues located between the eighth and ninth abdominal segments in heliothines and B. mori.Injection or administration of PBAN into intact female moths, isolated abdomens, or in vitro cultured PG stimulates pheromone production by the PG.In Helicoverpa armigera, PBAN is known to regulate the production of the hairpencil pheromone in males.When the larvae of some kinds of armyworms grow under crowded conditions, their cuticle is heavily melanized. MRCH is responsible for melanin synthesis in this process, but the mode of action of this hormone is not yet fully understood.
Pheromonotropin Preparation Products And Raw materials
Raw materials
Preparation Products
Pheromonotropin Suppliers
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