ChemicalBook > CAS DataBase List > CL 316243
CL 316243
- Product Name
- CL 316243
- CAS No.
- 138908-40-4
- Chemical Name
- CL 316243
- Synonyms
- CL 316243;CL-316243 sodium;CL 316,243 hydrate;COLLAGEN FROM HUMAN LUNG;CL 316243 disodium (CL316243 disodium);inhibit,Adrenergic Receptor,CL 316243,Inhibitor,Beta Receptor,CL-316243,CL316243;Disodium 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate;Disodium 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate hydrate
- CBNumber
- CB4503291
- Molecular Formula
- C20H18ClNO7.2Na
- Formula Weight
- 465.795
- MOL File
- 138908-40-4.mol
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CL 316243 Property
- storage temp.
- room temp
- solubility
- H2O: >10 mg/mL
- form
- solid
- color
- white
- Water Solubility
- Soluble to 100 mM in water
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- C5976
- Product name
- CL 316,243 hydrate
- Purity
- ≥98% (HPLC), powder
- Packaging
- 5mg
- Price
- $267
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- C5976
- Product name
- CL 316,243 hydrate
- Purity
- ≥98% (HPLC), powder
- Packaging
- 25mg
- Price
- $1080
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17499
- Product name
- CL 316,243
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $32
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17499
- Product name
- CL 316,243
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $55
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17499
- Product name
- CL 316,243
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $139
- Updated
- 2024/03/01
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CL 316243 Chemical Properties,Usage,Production
Uses
CL 316243 Disodium Salt is a potent and highly selective β3-adrenoceptor agonist.
Uses
CL 316,243 hydrate has been used:
- as a β-agonists to inject mice and study its effect on the expression of mammalian major facilitator superfamily domain-containing protein (Mfsd2a)
- as an adrenergic agonist to stimulate adrenergic response in order to study the metabolic activity of brown, beige and white adipose tissues in mice
- as a β3-adrenergic agonist to inject mice for in vivo lipolytic challenge
Hazard
A poison.
Biochem/physiol Actions
β Adrenoceptor is expressed in a number of tissues such as heart, adipose tissue, colon and other tissues. It is associated with many different biological functions. β Adrenoceptor fills in as an objective for treating type 2 diabetes, heart failure, cachexia, obesity, metabolic disorder, issues related with bladder, colon and malignant tumor growth. Depression and anxiety can also be treated via β adrenoceptor. CL 316,243 is known to have antidiabetic action via β adrenoceptor. It is a potent stimulator of lipolysis. It also activates β3- adrenoceptors on neurons in hypothalamic areas that are important in the central regulation of appetite.
storage
Store at -20°C
CL 316243 Preparation Products And Raw materials
Raw materials
Preparation Products
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