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L-CYSTEINESULFINIC ACID MONOHYDRATE

Product Name
L-CYSTEINESULFINIC ACID MONOHYDRATE
CAS No.
207121-48-0
Chemical Name
L-CYSTEINESULFINIC ACID MONOHYDRATE
Synonyms
3-sulfino-l-alanine;Sulfino-L-alanine hydrate;L-Cysteinesulfinic Acid (hydrate);(2R)-2-aMino-3-sulfinopropanoic acid;L-Cysteinesulfinic acid Monohydrate 99%;(1R)-1-amino-2-mercaptoethanesulfinic acid hydrate;L Cysteinesulfinic acid monohydrate,LCysteinesulfinic acid monohydrate,Metabotropic glutamate receptors,Inhibitor,L-Cysteinesulfinic acid,inhibit,mGluR
CBNumber
CB4503615
Molecular Formula
HO2SCH2CH(NH2)CO2HH2O
Formula Weight
171.17
MOL File
207121-48-0.mol
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L-CYSTEINESULFINIC ACID MONOHYDRATE Property

Melting point:
163 °C (dec.)(lit.)
storage temp. 
-20°C
solubility 
Aqueous Acid (Slightly), Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
optical activity
[α]25/D +24°, c = 1 in 1 M HCl
Stability:
Temperature Sensitive
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
2930901300
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
270881
Product name
L-Cysteinesulfinic acid monohydrate
Purity
99%
Packaging
1g
Price
$796
Updated
2024/03/01
Sigma-Aldrich
Product number
270881
Product name
L-Cysteinesulfinic acid monohydrate
Purity
99%
Packaging
250mg
Price
$201
Updated
2023/06/20
Cayman Chemical
Product number
29597
Product name
L-Cysteinesulfinic Acid (hydrate)
Packaging
50mg
Price
$61
Updated
2024/03/01
Cayman Chemical
Product number
29597
Product name
L-Cysteinesulfinic Acid (hydrate)
Packaging
100mg
Price
$111
Updated
2024/03/01
Sigma-Aldrich
Product number
C4418
Product name
L-Cysteinesulfinic acid monohydrate
Packaging
100mg
Price
$134
Updated
2024/03/01
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L-CYSTEINESULFINIC ACID MONOHYDRATE Chemical Properties,Usage,Production

Description

L-Cysteinesulfinic acid is an excitatory amino acid and agonist of metabotropic glutamate receptors (mGluRs). It increases intracellular inositol phosphate levels in CHO cells expressing mGluR1, mGluR5, or mGluR8 (EC50s = 120, 30, and 110 μM, respectively) and inhibits forskolin-induced cAMP production in CHO cells expressing mGluR2 or mGluR6 and hamster kidney cells expressing mGluR4 (EC50s = 100, 100, and 2,000 μM, respectively). It selectively binds to mGluR1α (Ki = 3,510 nM) over adrenergic, dopamine, histamine, muscarinic, nicotinic, or serotonin receptors (Kis = >10,000 nM for all). L-Cysteinesulfinic acid (1 mM) decreases mean arterial blood pressure and heart rate in rats when microinjected into the nucleus tractus solitarius (NTS). L-Cysteinesulfinic acid can be formed via oxidation of L-cysteine by reactive oxygen species (ROS), and conversion of cysteine to L-cysteinesulfinic acid in cysteine-containing peptide probes has been used to measure oxidative stress.

Chemical Properties

Off-White Solid

Uses

An amino acid derivative with neuropathological interest; Putative excitatory amino acid neurotransmitter.

Uses

L-Cysteinesulfinic acid monohydrate has been used in the fluorescence measurement of cysteine oxidation.

Biochem/physiol Actions

Cysteinesulfinic acid (CSA), also called 3-sulfinoalanine is synthesized by the conversion of sulfur to sulfinic acid in cysteine by the enzyme cysteine dioxygenase (CDO). CSA is a putative excitatory amino acid (EAA) with neurotransmitter functionality. It also regulates cardiovascular functions.

L-CYSTEINESULFINIC ACID MONOHYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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L-CYSTEINESULFINIC ACID MONOHYDRATE Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
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View Lastest Price from L-CYSTEINESULFINIC ACID MONOHYDRATE manufacturers

Hong Kong Tiansheng New Material Trading Co., Ltd
Product
L-Cysteinesulfinic acid monohydrate 207121-48-0
Price
US $1.90/g
Min. Order
1Kg/Bag
Purity
99%
Supply Ability
19tons
Release date
2021-12-09

207121-48-0, L-CYSTEINESULFINIC ACID MONOHYDRATERelated Search:


  • (2R)-2-aMino-3-sulfinopropanoic acid
  • L-Cysteinesulfinic acid Monohydrate 99%
  • 3-sulfino-l-alanine
  • (1R)-1-amino-2-mercaptoethanesulfinic acid hydrate
  • L-Cysteinesulfinic Acid (hydrate)
  • Sulfino-L-alanine hydrate
  • L Cysteinesulfinic acid monohydrate,LCysteinesulfinic acid monohydrate,Metabotropic glutamate receptors,Inhibitor,L-Cysteinesulfinic acid,inhibit,mGluR
  • 207121-48-0
  • HO2SCH2CHNH2CO2HH2O
  • Amino Acids & Derivatives
  • Sulfur & Selenium Compounds