TAUTOMYCETIN SOLUTION
- Product Name
- TAUTOMYCETIN SOLUTION
- CAS No.
- 119757-73-2
- Chemical Name
- TAUTOMYCETIN SOLUTION
- Synonyms
- TAUTOMYCETIN SOLUTION;Tautomycetin (10mg/mL in DMSO) DISCONTINUED;(1R*,2S*)-16-Ethyl-3,7-dihydroxy-1,2,6,10,12-pentamethyl-5,14-dioxo-15,17-octadecadienyl2,5-dihydro-β-hydroxy-4-methyl-2,5-dioxo-3-furanpropanoicacidester;3-hydroxy-3-(4-methyl-2,5-dioxo-2,5-dihydro-furan-3-yl)propionic acid 16-ethyl-3,7-dihydroxy-1,2,6,10,12-pentamethyl-5,14-dioxooctadeca-15,17-dienyl ester solution;(1R,2S,3R,6S,7S,10S,12R,15E,βR,3R)-16-Ethyl-3,7-dihydroxy-1,2,6,10,12-pentamethyl-5,14-dioxo-15,17-octadecadienyl 2,5-dihydro-β-hydroxy-4-methyl-2,5-dioxo-3-furanpropanoic acid ester;3-Furanpropanoic acid, 2,5-dihydro-β-hydroxy-4-methyl-2,5-dioxo-, (1R,2S,6S,7S,10S,12R,15E)-16-ethyl-3,7-dihydroxy-1,2,6,10,12-pentamethyl-5,14-dioxo-15,17-octadecadien-1-yl ester, (βR)-
- CBNumber
- CB4504894
- Molecular Formula
- C33H50O10
- Formula Weight
- 606.75
- MOL File
- 119757-73-2.mol
TAUTOMYCETIN SOLUTION Property
- Boiling point:
- 763.7±60.0 °C(Predicted)
- Density
- 1.148±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMSO: 10 mg/mL
- form
- Colourless liquid
- pka
- 12.36±0.20(Predicted)
- color
- colorless
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H300Fatal if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B7009
- Product name
- Tautomycetin
- Packaging
- 50ug
- Price
- $511
- Updated
- 2021/12/16
TAUTOMYCETIN SOLUTION Chemical Properties,Usage,Production
Uses
Tautomycetin induces apoptosis by inactivating Akt through a PP1-independent signaling pathway in human breast cancer cells. Tautomycin is closely related to another anhydride containing polyketide PP inhibitor called Tautomycetin which, in addition to being useful as a lead for cancer drug discovery, also is a very potent immunosuppressor.
Definition
ChEBI: Tautomycetin is a sesquiterpenoid.
Biological Activity
Potent activated T cell-specific immunosuppressor. Selectively inhibits PP1 over PP2 with IC 50 values of 1.6 and 62 nM respectively. Active in vivo .
TAUTOMYCETIN SOLUTION Preparation Products And Raw materials
Raw materials
Preparation Products
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