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2-Bromo-5-(trifluoromethyl)benzaldehyde

Product Name
2-Bromo-5-(trifluoromethyl)benzaldehyde
CAS No.
102684-91-3
Chemical Name
2-Bromo-5-(trifluoromethyl)benzaldehyde
Synonyms
4-Bromo-3-formylbenzotrifluoride;2-Bromo-5-(trifluoromethyl)benzaldehyde;1-(4-Amino-2-hydroxyphenyl)ethane-2-one;Benzaldehyde, 2-bromo-5-(trifluoromethyl)-;2-Bromo-5-(trifluoromethyl)benzaldehyde >2-BroMo-5-(trifluoroMethyl)benzaldehyde, 95+%;4-Bromo-3-formylbenzotrifluoride, 6-Bromo-alpha,alpha,alpha-trifluoro-m-tolualdehyde
CBNumber
CB4507178
Molecular Formula
C8H4BrF3O
Formula Weight
253.02
MOL File
102684-91-3.mol
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2-Bromo-5-(trifluoromethyl)benzaldehyde Property

Boiling point:
239.1±35.0 °C(Predicted)
Density 
1.677±0.06 g/cm3(Predicted)
refractive index 
1.511
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
clear liquid
color 
Colorless to Light yellow to Light orange
Sensitive 
Air Sensitive
InChI
InChI=1S/C8H4BrF3O/c9-7-2-1-6(8(10,11)12)3-5(7)4-13/h1-4H
InChIKey
CSOBJYGHQOLWOD-UHFFFAOYSA-N
SMILES
C(=O)C1=CC(C(F)(F)F)=CC=C1Br
CAS DataBase Reference
102684-91-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Hazard Note 
Irritant
HS Code 
2913000090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B4508
Product name
2-Bromo-5-(trifluoromethyl)benzaldehyde
Purity
>97.0%(GC)
Packaging
1g
Price
$30
Updated
2025/07/31
TCI Chemical
Product number
B4508
Product name
2-Bromo-5-(trifluoromethyl)benzaldehyde
Purity
>97.0%(GC)
Packaging
5g
Price
$120
Updated
2025/07/31
TRC
Product number
B699990
Product name
2-Bromo-5-(trifluoromethyl)benzaldehyde
Packaging
10mg
Price
$45
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
B2057
Product name
2-Bromo-5-(trifluoromethyl)benzaldehyde
Purity
97%
Packaging
1g
Price
$7
Updated
2021/12/16
Matrix Scientific
Product number
072689
Product name
2-Bromo-5-(trifluoromethyl)benzaldehyde
Purity
95+%
Packaging
1g
Price
$10
Updated
2021/12/16
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2-Bromo-5-(trifluoromethyl)benzaldehyde Chemical Properties,Usage,Production

Chemical Properties

Pale yellow liquid

Synthesis

To a solution of the 2-bromo-5-trifluoromethyl-benzonitrile (2.6 g, 10.4 mmol) in toluene (20 mL) at -78° C. was added diisobutylaluminium hydride (21 mL, 21 mmol, 1.0 M in toluene) cooled to -78° C. by cannula. The solution was stirred at -78 to -50° C. for 2 hours. Water (5 mL) was added slowly to the reaction and the reaction was allowed to warm up to room temperature. The mixture was adjusted to pH 10 with NaOH. The product was extracted with dichloromethane, washed with saturated sodium bicarbonate and brine, dried over sodium sulfate and concentrated. The residue was purified by flash chromatography (hexanes/ether 90:10) to give 2-Bromo-5-(trifluoromethyl)benzaldehyde (2.0 g, 76 %) as a dark solid.

References

[1] Journal of Medicinal Chemistry, 1986, vol. 29, # 8, p. 1442 - 1452
[2] Patent: US2007/21408, 2007, A1. Location in patent: Page/Page column 130-131
[3] ACS Medicinal Chemistry Letters, 2010, vol. 1, # 9, p. 483 - 487
[4] Patent: US2005/261310, 2005, A1. Location in patent: Page/Page column 24

2-Bromo-5-(trifluoromethyl)benzaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Bromo-5-(trifluoromethyl)benzaldehyde Suppliers

Americas 1 China 166 Europe 1 France 1 Germany 2 India 6 Italy 1 Japan 1 The Netherlands 1 United Kingdom 7 United States 24 Global 211
Interchim SA
Tel
--
Fax
--
Email
him@interchim.com
Country
France
ProdList
2725
Advantage
58
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View Lastest Price from 2-Bromo-5-(trifluoromethyl)benzaldehyde manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Bromo-5-(trifluoromethyl)benzaldehyde 102684-91-3
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2025-03-10
Kindchem(Nanjing)Co.,Ltd
Product
2-Bromo-5-(trifluoromethyl)benzaldehyde 102684-91-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100
Release date
2024-01-02
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Bromo-5-(trifluoromethyl)benzaldehyde 102684-91-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

102684-91-3, 2-Bromo-5-(trifluoromethyl)benzaldehydeRelated Search:

2-BROMO-5-(TRIFLUOROMETHYL)BENZOIC ACID methyl 2-bromo-5-(trifluoromethyl)benzoate ethyl 2-bromo-5-(trifluoromethyl)benzoate 2-Bromo-5-(trifluoromethyl)benzaldehyde 2-bromo-5-(trifluoromethyl)benzamide 2-bromo-4-(trifluoromethyl)benzaldehyde 3-Bromo-5-(trifluoromethyl)benzaldehyde oxime,3-Bromo-5-(trifluoromethyl)benzaldehyde oxime 98% 2-BROMO-3-(TRIFLUOROMETHYL)BENZALDEHYDE 3-Bromo-5-(trifluoromethyl)benzaldehyde97%,3-BROMO-5-(TRIFLUOROMETHYL)BENZALDEHYDE 4-BROMO-2-(TRIFLUOROMETHYL)BENZALDEHYDE 2-Bromo-5-(trifluoromethyl)benzaldehyde minimum 4-BROMO-3-TRIFLUOROMETHYL-BENZALDEHYDE 2-bromo-5-(trifluoromethyl)benzaldehyde 95%

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  • 2-BroMo-5-(trifluoroMethyl)benzaldehyde, 95+%
  • 2-Bromo-5-(trifluoromethyl)benzaldehyde &gt
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  • 1-(4-Amino-2-hydroxyphenyl)ethane-2-one
  • 102684-91-3
  • C8H7BrF3O
  • C8H4OBrF3
  • Fluorine series
  • Aryl
  • Organohalides