(R)-BAY1238097

Product Name: (R)-BAY1238097
CAS No.: 1564269-85-7
Chemical Name: (R)-BAY1238097
Synonyms: (R)-BAY1238097;(R)BAY1238097,(R) BAY1238097,(R)-BAY-1238097;3H-2,3-Benzodiazepine-3-carboxamide, 4,5-dihydro-7,8-dimethoxy-N,4-dimethyl-1-[4-(4-methyl-1-piperazinyl)phenyl]-, (4R)-
CBNumber: CB45419641
Molecular Formula: C25H33N5O3
Formula Weight: 451.56
MOL File: 1564269-85-7.mol

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(R)-BAY1238097 Property

Density: 1.22±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 150 mg/mL (332.18 mM);Water : < 0.1 mg/mL (insoluble)
form: Solid
pka: 15.43±0.60(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0089882
Product name: (R)-BAY1238097
Purity: 99.61%
Packaging: 5mg
Price: $250
Updated: 2021/12/16

ChemScene

Product number: CS-0089882
Product name: (R)-BAY1238097
Purity: 99.61%
Packaging: 10mg
Price: $390
Updated: 2021/12/16

ChemScene

Product number: CS-0089882
Product name: (R)-BAY1238097
Purity: 99.61%
Packaging: 50mg
Price: $1250
Updated: 2021/12/16

ChemScene

Product number: CS-0089882
Product name: (R)-BAY1238097
Purity: 99.61%
Packaging: 100mg
Price: $2100
Updated: 2021/12/16

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(R)-BAY1238097 Chemical Properties,Usage,Production

Description

(R)-BAY1238097 is the R-isomer with lower activity of BAY1238097. BAY1238097 is a potent and selective inhibitor of BET binding to histones and has strong anti-proliferative activity in different AML (acute myeloid leukemia) and MM (multiple myeloma) models through down-regulation of c-Myc levels and its downstream transcriptome[1][2]. BET[1].

References

[1]. Lejeune, P., et al. (2015) Abstract 3524: BAY 1238097, a novel BET inhibitor with strong efficacy in hematological tumor models. Cancer Research, 75(15 Suppl), 884. [2]. Bernasconi E, et al. Preclinical evaluation of the BET bromodomain inhibitor BAY 1238097 for the treatment of lymphoma. Br J Haematol. 2017 Sep;178(6):936-948.

(R)-BAY1238097 Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-BAY1238097 Suppliers

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1564269-85-7, (R)-BAY1238097Related Search:

(R)-BAY1238097

3H-2,3-Benzodiazepine-3-carboxamide, 4,5-dihydro-7,8-dimethoxy-N,4-dimethyl-1-[4-(4-methyl-1-piperazinyl)phenyl]-, (4R)-

(R)BAY1238097,(R) BAY1238097,(R)-BAY-1238097

1564269-85-7