2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine

Product Name: 2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine
CAS No.: 722515-03-9
Chemical Name: 2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine
Synonyms: 2’-Chloro-N6-(4-trifluoromethyl)benzyladenosine;2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine;Adenosine, 2-chloro-N-[[4-(trifluoromethyl)phenyl]methyl]- (9CI);(2R,3R,4S,5R)-2-(2-chloro-6-((4-(trifluoromethyl)benzyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
CBNumber: CB45493052
Molecular Formula: C18H17ClF3N5O4
Formula Weight: 459.81
MOL File: 722515-03-9.mol

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2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine Property

Boiling point:: 629.7±65.0 °C(Predicted)
Density: 1.77±0.1 g/cm3(Predicted)
pka: 13.05±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine Chemical Properties,Usage,Production

Uses

2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
[2] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine Preparation Products And Raw materials

Raw materials

Preparation Products

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2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine Suppliers

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722515-03-9, 2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosineRelated Search:

2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine

Adenosine, 2-chloro-N-[[4-(trifluoromethyl)phenyl]methyl]- (9CI)

2’-Chloro-N6-(4-trifluoromethyl)benzyladenosine

(2R,3R,4S,5R)-2-(2-chloro-6-((4-(trifluoromethyl)benzyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

722515-03-9