ChemicalBook > CAS DataBase List > EC-5026

EC-5026

Product Name: EC-5026
CAS No.: 1809885-32-2
Chemical Name: EC-5026
Synonyms: EC-5062;EC-5026;BPN-19186;EC-5026 (BPN-19186);EC5026, 10 mM in DMSO;(S)-1-[3-Fluoro-4-(trifluoromethoxy)phenyl]-3-[1-(2-methylbutanoyl)-4-piperidyl]urea;(S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-3-(1-(2-methylbutanoyl)piperidin-4-yl)urea;1-[3-fluoro-4-(trifluoromethoxy)phenyl]-3-{1-[(2S)-2-methylbutanoyl]piperidin-4-yl}urea;Urea, N-[3-fluoro-4-(trifluoromethoxy)phenyl]-N'-[1-[(2S)-2-methyl-1-oxobutyl]-4-piperidinyl]-;sEH,EC5026,analgesic,BPN 19186,Epoxide Hydrolase,pain,inhibit,Hydrolase,anti-inflammatory,BPN19186,Inhibitor,EC-5026,EC 5026,mediators,Epoxide,Soluble
CBNumber: CB45831339
Molecular Formula: C18H23F4N3O3
Formula Weight: 405.39
MOL File: 1809885-32-2.mol

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EC-5026 Property

Boiling point:: 466.8±45.0 °C(Predicted)
Density: 1.30±0.1 g/cm3(Predicted)
solubility: DMSO:250.0(Max Conc. mg/mL);616.69(Max Conc. mM)
form: A solid
pka: 12.94±0.20(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0113694
Product name: EC5026
Purity: 98.01%
Packaging: 5mg
Price: $90
Updated: 2021/12/16

ChemScene

Product number: CS-0113694
Product name: EC5026
Purity: 98.01%
Packaging: 10mg
Price: $150
Updated: 2021/12/16

ChemScene

Product number: CS-0113694
Product name: EC5026
Purity: 98.01%
Packaging: 25mg
Price: $250
Updated: 2021/12/16

ChemScene

Product number: CS-0113694
Product name: EC5026
Purity: 98.01%
Packaging: 50mg
Price: $450
Updated: 2021/12/16

ChemScene

Product number: CS-0113694
Product name: EC5026
Purity: 98.01%
Packaging: 100mg
Price: $750
Updated: 2021/12/16

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EC-5026 Chemical Properties,Usage,Production

Uses

EC5026 (BPN-19186) is a first-in-class, non-opioid and orally active soluble Epoxide Hydrolase (sEH) inhibitor. EC5026 shows efficacy for inflammatory and neuropathic pain[1].

in vivo

EC5026 (BPN-19186) has already shown efficacy for treating pain with no apparent adverse or addictive effects in laboratory animals and relieving naturally occurring pain in dogs, cats and horses^[1].

References

[1] EicOsis Announces FDA Acceptance of IND Application for EC5026, the First Soluble Epoxide Hydrolase Inhibitor to Treat Pain.2019.

EC-5026 Preparation Products And Raw materials

Raw materials

Preparation Products

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EC-5026 Suppliers

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1809885-32-2, EC-5026Related Search:

EC-5026

EC-5062

BPN-19186

Urea, N-[3-fluoro-4-(trifluoromethoxy)phenyl]-N'-[1-[(2S)-2-methyl-1-oxobutyl]-4-piperidinyl]-

EC-5026 (BPN-19186)

(S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-3-(1-(2-methylbutanoyl)piperidin-4-yl)urea

sEH,EC5026,analgesic,BPN 19186,Epoxide Hydrolase,pain,inhibit,Hydrolase,anti-inflammatory,BPN19186,Inhibitor,EC-5026,EC 5026,mediators,Epoxide,Soluble

(S)-1-[3-Fluoro-4-(trifluoromethoxy)phenyl]-3-[1-(2-methylbutanoyl)-4-piperidyl]urea

1-[3-fluoro-4-(trifluoromethoxy)phenyl]-3-{1-[(2S)-2-methylbutanoyl]piperidin-4-yl}urea

EC5026, 10 mM in DMSO

1809885-32-2

C18H23F4N3O3