VBIT-12

Product Name: VBIT-12
CAS No.: 2089227-65-4
Chemical Name: VBIT-12
Synonyms: VBIT-12;VBIT 12,VBIT12;VBIT-12 ，S8936;VBIT-12, 10 mM in DMSO;N-[[1-(1-naphthalenylmethyl)-4-(phenylamino)-4-piperidinyl]carbonyl]-glycine;Glycine, N-[[1-(1-naphthalenylmethyl)-4-(phenylamino)-4-piperidinyl]carbonyl]-
CBNumber: CB45831874
Molecular Formula: C25H27N3O3
Formula Weight: 417.5
MOL File: 2089227-65-4.mol

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VBIT-12 Property

Boiling point:: 698.0±55.0 °C(Predicted)
Density: 1.286±0.06 g/cm3(Predicted)
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 15 mg/ml
form: A crystalline solid
pka: 3.65±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

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VBIT-12 Chemical Properties,Usage,Production

Uses

VBIT-12 is a potent VDAC1 inhibitor. VBIT-12 directly interacts with VDAC1 and prevents VDAC1 oligomerization, and thus inhibits apoptotic action of VDAC1[1].

References

[1] Shoshan-Barmatz V, et al. VDAC1, mitochondrial dysfunction, and Alzheimer's disease. Pharmacol Res. 2018 May;131:87-101. DOI:10.1016/j.phrs.2018.03.010

VBIT-12 Preparation Products And Raw materials

Raw materials

Preparation Products

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VBIT-12 Suppliers

China 45 United States 4 Global 49

Shanghai Lollane Biological Technology Co.,Ltd.

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2089227-65-4, VBIT-12Related Search:

VBIT-12

Glycine, N-[[1-(1-naphthalenylmethyl)-4-(phenylamino)-4-piperidinyl]carbonyl]-

VBIT 12,VBIT12

N-[[1-(1-naphthalenylmethyl)-4-(phenylamino)-4-piperidinyl]carbonyl]-glycine

VBIT-12, 10 mM in DMSO

VBIT-12 ，S8936

2089227-65-4