DHODH-IN-11
- Product Name
- DHODH-IN-11
- CAS No.
- 1263303-95-2
- Chemical Name
- DHODH-IN-11
- Synonyms
- DHODH-IN-11;DHODH-IN-11 ，S0747;Acetamide, N-[1,1'-biphenyl]-4-yl-2-cyano-2-(hydroxyimino)-, (2E)-;(E)-2-([1,1'-Biphenyl]-4-ylamino)-N-hydroxy-2-oxoacetimidoyl cyanide;antiinflammatory,DHODH IN 11,Inhibitor,Leflunomide,Rat,DHODHIN11,DNA/RNA Synthesis,cyano-oximes,Dihydroorotate Dehydrogenase,inhibit,DHODH
- CBNumber
- CB45855429
- Molecular Formula
- C15H11N3O2
- Formula Weight
- 265.27
- MOL File
- 1263303-95-2.mol
DHODH-IN-11 Property
- Density
- 1.21±0.1 g/cm3(Predicted)
- storage temp.
- -20°C, protect from light
- solubility
- DMSO: 125 mg/mL (471.22 mM)
- form
- A solid
- pka
- 7.63±0.10(Predicted)
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CS-0113745
- Product name
- DHODH-IN-11
- Purity
- 99.94%
- Packaging
- 5mg
- Price
- $120
- Updated
- 2021/12/16
- Product number
- CS-0113745
- Product name
- DHODH-IN-11
- Purity
- 99.94%
- Packaging
- 10mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- CS-0113745
- Product name
- DHODH-IN-11
- Purity
- 99.94%
- Packaging
- 25mg
- Price
- $380
- Updated
- 2021/12/16
- Product number
- CS-0113745
- Product name
- DHODH-IN-11
- Purity
- 99.94%
- Packaging
- 50mg
- Price
- $600
- Updated
- 2021/12/16
- Product number
- CS-0113745
- Product name
- DHODH-IN-11
- Purity
- 99.94%
- Packaging
- 100mg
- Price
- $950
- Updated
- 2021/12/16
DHODH-IN-11 Chemical Properties,Usage,Production
Uses
DHODH-IN-11 (Compound 14b) is a Leflunomide derivative and a weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03[1].
References
[1] Giorgis M, et al. 1,2,5-Oxadiazole analogues of leflunomide and related compounds. Eur J Med Chem. 2011 Jan;46(1):383-92. DOI:10.1016/j.ejmech.2010.10.029
DHODH-IN-11 Preparation Products And Raw materials
Raw materials
Preparation Products
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