ChemicalBook > CAS DataBase List > Alloc-Val-Ala-PAB-PNP
Alloc-Val-Ala-PAB-PNP
- Product Name
- Alloc-Val-Ala-PAB-PNP
- CAS No.
- 1884578-27-1
- Chemical Name
- Alloc-Val-Ala-PAB-PNP
- Synonyms
- Alloc-Val-Ala-PAB-PNP;L-Alaninamide, N-[(2-propen-1-yloxy)carbonyl]-L-valyl-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-
- CBNumber
- CB45864728
- Molecular Formula
- C26H30N4O9
- Formula Weight
- 542.54
- MOL File
- 1884578-27-1.mol
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Alloc-Val-Ala-PAB-PNP Property
- Boiling point:
- 799.1±60.0 °C(Predicted)
- Density
- 1.296±0.06 g/cm3(Predicted)
- pka
- 11.52±0.46(Predicted)
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Alloc-Val-Ala-PAB-PNP Chemical Properties,Usage,Production
Description
Alloc-Val-Ala-PAB-PNP is a peptide linker with a terminal 4-Nitrophenol group and an Alloc protecting group. The peptide chain can act as a cleavable linker in drug design, such as in antibody drug conjugates (ADC). In peptide synthesis, carboxylate ester derivatives of 4-nitrophenol may serve as activated components for construction of amide moieties. The Alloc group is stable to treatment with piperidine and TFA, and can be removed in neutral conditions with catalytic amounts of Pd(PPh3)4 in the presence of PhSiH3. This allows the allyl system to work orthogonality with the most common protecting groups.
Alloc-Val-Ala-PAB-PNP Preparation Products And Raw materials
Raw materials
Preparation Products
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Alloc-Val-Ala-PAB-PNP Suppliers
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View Lastest Price from Alloc-Val-Ala-PAB-PNP manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Alloc-Val-Ala-PAB-PNP 1884578-27-1
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >95.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-29