ChemicalBook > CAS DataBase List > 1-Propanone, 1-[(5R)-4,5-dihydro-5-phenyl-1H-pyrazol-1-yl]-2,2-dimethyl-
1-Propanone, 1-[(5R)-4,5-dihydro-5-phenyl-1H-pyrazol-1-yl]-2,2-dimethyl-
- Product Name
- 1-Propanone, 1-[(5R)-4,5-dihydro-5-phenyl-1H-pyrazol-1-yl]-2,2-dimethyl-
- CAS No.
- 2049872-86-6
- Chemical Name
- 1-Propanone, 1-[(5R)-4,5-dihydro-5-phenyl-1H-pyrazol-1-yl]-2,2-dimethyl-
- Synonyms
- GSK'962;GSK-962,GSK962;GSK962, 10 mM in DMSO;2,2-dimethyl-1-[(5R)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl]propan-1-one;1-Propanone, 1-[(5R)-4,5-dihydro-5-phenyl-1H-pyrazol-1-yl]-2,2-dimethyl-
- CBNumber
- CB45889264
- Molecular Formula
- C14H18N2O
- Formula Weight
- 230.31
- MOL File
- 2049872-86-6.mol
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1-Propanone, 1-[(5R)-4,5-dihydro-5-phenyl-1H-pyrazol-1-yl]-2,2-dimethyl- Property
- Boiling point:
- 342.8±45.0 °C(Predicted)
- Density
- 1.06±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO:75.0(Max Conc. mg/mL);325.65(Max Conc. mM)
- form
- Solid
- pka
- 0.98±0.40(Predicted)
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
TRC
- Product number
- G797813
- Product name
- GSK''962
- Packaging
- 1mg
- Price
- $220
- Updated
- 2021/12/16
TRC
- Product number
- G797813
- Product name
- GSK''962
- Packaging
- 2.5mg
- Price
- $440
- Updated
- 2021/12/16
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1-Propanone, 1-[(5R)-4,5-dihydro-5-phenyl-1H-pyrazol-1-yl]-2,2-dimethyl- Chemical Properties,Usage,Production
Uses
GSK''962 is an inactive enantiomer of GSK''963, which is a novel highly potent and selective RIP1 inhibitor.
Biological Activity
GSKμ962 (GSKμ962A) corresponds to the inactive (R)-enantiomer of the highly potent and selective RIPK1 (RIP1) inhibitor GSKμ963 (GSKμ963A). GSKμ962 serves as an ideal GSKμ963 negative control compound for probing RIPK1-mediated responses both in vitro and in vivo.
1-Propanone, 1-[(5R)-4,5-dihydro-5-phenyl-1H-pyrazol-1-yl]-2,2-dimethyl- Preparation Products And Raw materials
Raw materials
Preparation Products
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