d-Epigalbacin

Product Name: d-Epigalbacin
CAS No.: 84709-25-1
Chemical Name: d-Epigalbacin
Synonyms: epigalbacin;d-epigalacin;(-)-Zuonin A;d-Epigalbacin;1,3-Benzodioxole, 5,5'-[(2S,3R,4S,5S)-tetrahydro-3,4-dimethyl-2,5-furandiyl]bis-
CBNumber: CB45985179
Molecular Formula: C20H20O5
Formula Weight: 340.37
MOL File: 84709-25-1.mol

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d-Epigalbacin Property

Boiling point:: 460.6±45.0 °C(Predicted)
Density: 1.258±0.06 g/cm3(Predicted)
storage temp.: 4°C, protect from light
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0119326
Product name: (-)-ZuoninA
Purity: 99.84%
Packaging: 1mg
Price: $200
Updated: 2021/12/16

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d-Epigalbacin Chemical Properties,Usage,Production

Biological Activity

(-)-Zuonin A (D-Epigalbacin), a natural lignin, is a potent and selective inhibitor of JNKs with IC50 values of 1.7 μM, 2.9 μM and 1.74 μM for JNK1, JNK2 and JNK3, respectively.

in vitro

(?)-zuonin A binds the D-recruitment site (DRS) of JNK, a recruitment site utilized by substrates and other substrates to dock onto and recognize MAPKs.
(?)-zuonin A

target

JNK1

1.7 μM (IC ₅₀ )

JNK2

2.9 μM (IC ₅₀ )

JNK3

1.74 μM (IC ₅₀ )

d-Epigalbacin Preparation Products And Raw materials

Raw materials

Preparation Products

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d-Epigalbacin

epigalbacin

1,3-Benzodioxole, 5,5'-[(2S,3R,4S,5S)-tetrahydro-3,4-dimethyl-2,5-furandiyl]bis-

(-)-Zuonin A

d-epigalacin

84709-25-1