ETHYL 3-AMINO-3-THIOXOPROPANOATE
- Product Name
- ETHYL 3-AMINO-3-THIOXOPROPANOATE
- CAS No.
- 13621-50-6
- Chemical Name
- ETHYL 3-AMINO-3-THIOXOPROPANOATE
- Synonyms
- Ethyl thiocarbamoylacetate;(Ethoxycarbonyl)thioacetamide;ETHYL 3-AMINO-3-THIOXOPROPANOATE;alpha-Ethoxycarbonylthioacetamide; ETHYL 3-1AMINO-3-THIOXOPROPANOATE;THIOCARBAMOYL ACETIC ACID ETHYL ESTER;ethyl 3-amino-3-sulfanylidenepropanoate;Propanoic acid,3-amino-3-thioxo-, ethyl ester;ETHYL 3-AMINO-3-THIOXOPROPANOATE ISO 9001：2015 REACH;THIOCARBAMOYL ACETIC ACID ETHYL ESTER
ETHYL 3-AMINO-3-THIOXOPROPANOATE - CBNumber
- CB4684675
- Molecular Formula
- C5H9NO2S
- Formula Weight
- 147.2
- MOL File
- 13621-50-6.mol
ETHYL 3-AMINO-3-THIOXOPROPANOATE Property
- Melting point:
- 78-79℃
- Boiling point:
- 233℃
- Density
- 1.194
- Flash point:
- 95℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 12.71±0.29(Predicted)
- Appearance
- Light yellow to yellow Solid
- InChI
- InChI=1S/C5H9NO2S/c1-2-8-5(7)3-4(6)9/h2-3H2,1H3,(H2,6,9)
- InChIKey
- IBHOWDPRDYMIMO-UHFFFAOYSA-N
- SMILES
- C(OCC)(=O)CC(N)=S
N-Bromosuccinimide Price
- Product number
- E899733
- Product name
- Ethyl3-amino-3-thioxopropanoate
- Packaging
- 250mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- 449046
- Product name
- Ethyl 3-amino-3-thioxopropanoate
- Packaging
- 100mg
- Price
- $305
- Updated
- 2021/12/16
- Product number
- 6448AA
- Product name
- Ethyl3-amino-3-thioxopropanoate
- Packaging
- 5g
- Price
- $371
- Updated
- 2021/12/16
- Product number
- CHM0118829
- Product name
- ETHYL 3-AMINO-3-THIOXOPROPANOATE
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $1119.71
- Updated
- 2021/12/16
- Product number
- CHM0118829
- Product name
- ETHYL 3-AMINO-3-THIOXOPROPANOATE
- Purity
- 95.00%
- Packaging
- 50G
- Price
- $5234.25
- Updated
- 2021/12/16
ETHYL 3-AMINO-3-THIOXOPROPANOATE Chemical Properties,Usage,Production
Synthesis
105-56-6
13621-50-6
Step A: Ethyl cyanoacetate (4.7 mL, 44.3 mmol) was dissolved in a pyridine/triethylamine solvent mixture (500 mL, 1:1 v/v) under nitrogen protection. Hydrogen sulfide gas (H2S) was slowly passed into the solution until saturation. The reaction mixture was heated to 60 °C and stirred for 18 hours. After completion of the reaction, the solvent was evaporated under reduced pressure. The residue was separated by extraction with ethyl acetate (EtOAc) and dilute hydrochloric acid aqueous solution. The organic layer was dried with anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure. Removal of residual solid impurities by filtration afforded ethyl 3-amino-3-thiopropionate (6.25 g, 96% yield) as an orange oil. The product was characterized by 1H NMR (500 MHz, CDCl3): δ 8.92 (1H, broad single peak), 7.75 (1H, broad single peak), 4.21 (2H, quadruple peak, J = 7 Hz), 3.82 (2H, single peak), 1.29 (3H, triple peak, J = 7 Hz).
References
[1] Patent: WO2013/101974, 2013, A1. Location in patent: Paragraph 00704; 00705
[2] Patent: US9617268, 2017, B2. Location in patent: Page/Page column 347; 348
[3] Synlett, 2009, # 14, p. 2338 - 2340
[4] Phosphorus, Sulfur and Silicon and the Related Elements, 1994, vol. 96, # 1-4, p. 325 - 326
[5] Helvetica Chimica Acta, 1948, vol. 31, p. 1342,1348
ETHYL 3-AMINO-3-THIOXOPROPANOATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from ETHYL 3-AMINO-3-THIOXOPROPANOATE manufacturers
- Product
- ETHYL 3-AMINO-3-THIOXOPROPANOATE 13621-50-6
- Price
- US $9.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-27