ChemicalBook > CAS DataBase List > H-TYR-PHE-OH

H-TYR-PHE-OH

Product Name
H-TYR-PHE-OH
CAS No.
17355-11-2
Chemical Name
H-TYR-PHE-OH
Synonyms
TYR-PHE;YF;H-TYR-PHE-OH;tyr-phecrystalline;TYR-PHE 99+% CRYSTALLINE;L-TYROSYL-L-PHENYLALANINE;L-Phenylalanine, L-tyrosyl-;(S)-2-((S)-2-AMino-3-(4-hydroxyphenyl)propanaMido)-3-phenylpropanoic acid
CBNumber
CB4685713
Molecular Formula
C18H20N2O4
Formula Weight
328.36
MOL File
17355-11-2.mol
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H-TYR-PHE-OH Property

Boiling point:
642.2±55.0 °C(Predicted)
Density 
1.300±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
pka
3.40±0.10(Predicted)
form 
Solid
color 
White to off-white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T5379
Product name
Tyr-Phe
Packaging
250mg
Price
$93.8
Updated
2023/01/07
Chem-Impex
Product number
38801
Product name
Tyr-Phe-OH,98%(TLC)
Purity
98%(TLC)
Packaging
1G
Price
$170.24
Updated
2021/12/16
Chem-Impex
Product number
38801
Product name
Tyr-Phe-OH,98%(TLC)
Purity
98%(TLC)
Packaging
5G
Price
$680.96
Updated
2021/12/16
Chem-Impex
Product number
38801
Product name
Tyr-Phe-OH,≥98%(TLC)
Purity
≥98%(TLC)
Packaging
100MG
Price
$33.2
Updated
2021/12/16
Chem-Impex
Product number
38801
Product name
Tyr-Phe-OH,≥98%(TLC)
Purity
≥98%(TLC)
Packaging
250MG
Price
$66.39
Updated
2021/12/16
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H-TYR-PHE-OH Chemical Properties,Usage,Production

Uses

H-Tyr-Phe-OH (L-Tyrosyl-L-phenylalanine) is an orally active inhibitor of Angiotensin converting enzyme (ACE), with an inhibiton rate of 48% at 50 μM. H-Tyr-Phe-OH can be used as an biomarker for differentiating benign thyroid nodules (BTN) from thyroid cancer (TC). H-Tyr-Phe-OH exhibits xanthine oxidase inhibition (uric acid lowering) activity and serves as regulator in IL-8 production in neutrophil-like cells[1][2][3][4].

Definition

ChEBI: Tyr-Phe is a dipeptide formed from L-tyrosine and L-phenylalanine residues. It has a role as a metabolite.

References

[1] Zhu Wei, et al. Biomarker containing keratin type II cytoskeleton 1b for differentiating benign thyroid nodules and thyroid cancer: China, CN114264828A[P]. 2022-04-01.
[2] Enari Hiroyuki, et al. Angiotensin converting enzyme (ACE)-inhibiting peptides, ACE inhibitors containing the peptides, their uses, and manufacture of the peptides from shark cartilage: Japan, JP2005154326A[P]. 2005-06-16.
[3] Mao Xiangchao, et al. Method for preparing cod fish peptide with xanthine oxidase inhibitory activity: China, CN113005166A[P]. 2021-06-22.
[4] Hsueh PC, et al. Metabolomic profiling of parapneumonic effusion reveals a regulatory role of dipeptides in interleukin-8 production in neutrophil-like cells. Anal Chim Acta. 2020 Sep 1;1128:238-250. DOI:10.1016/j.aca.2020.06.022

H-TYR-PHE-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from H-TYR-PHE-OH manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
Tyr-Phe 17355-11-2
Price
US $2.00-5.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-20
Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Tyr-Phe 17355-11-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2024-03-13
Sichuan Jiaying Lai Technology Co.,LTD
Product
Tyr-Phe 17355-11-2
Price
US $1.00/g
Min. Order
1g
Purity
98%
Supply Ability
100KG
Release date
2019-07-29

17355-11-2, H-TYR-PHE-OHRelated Search:


  • H-TYR-PHE-OH
  • L-TYROSYL-L-PHENYLALANINE
  • TYR-PHE
  • TYR-PHE 99+% CRYSTALLINE
  • tyr-phecrystalline
  • (S)-2-((S)-2-AMino-3-(4-hydroxyphenyl)propanaMido)-3-phenylpropanoic acid
  • YF
  • L-Phenylalanine, L-tyrosyl-
  • 17355-11-2
  • Dipeptides and Tripeptides
  • Dipeptides
  • Biochemicals and Reagents
  • Amino Acids and Peptides
  • BioChemical
  • Amino Acid Derivatives
  • Dipeptides
  • Dipeptides and Tripeptides
  • Peptides