(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID

Product Name
(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID
CAS No.
909400-43-7
Chemical Name
(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID
Synonyms
CL-HIBO;ClHIBO,Cl HIBO;4-Chlorohomoibotenic acid;2-AMINO-3-(4-CHLORO-3-HYDROXYISOXAZOL-5-YL)PROPANOIC ACID;5-Isoxazolepropanoic acid, α-amino-4-chloro-2,3-dihydro-3-oxo-;(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID
CBNumber
CB4691192
Molecular Formula
C6H7ClN2O4
Formula Weight
206.58
MOL File
Mol file
More
Less

(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID Property

Density 
1.66±0.1 g/cm3(Predicted)
storage temp. 
Store at RT
pka
2.26±0.10(Predicted)
form 
Powder
Water Solubility 
Soluble to 20 mM in water
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Tocris
Product number
1673
Product name
Cl-HIBO
Purity
≥99%(HPLC)
Packaging
10
Price
$254
Updated
2021/12/16
Tocris
Product number
1673
Product name
Cl-HIBO
Purity
≥99%(HPLC)
Packaging
50
Price
$1050
Updated
2021/12/16
TRC
Product number
C853703
Product name
Cl-HIBO
Packaging
10mg
Price
$205
Updated
2021/12/16
TRC
Product number
C853703
Product name
Cl-HIBO
Packaging
25mg
Price
$405
Updated
2021/12/16
Usbiological
Product number
255003
Product name
Cl-HIBO
Packaging
10mg
Price
$531
Updated
2021/12/16
More
Less

(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID Chemical Properties,Usage,Production

Uses

The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA receptor), a heterotetrameric transmembrane receptor, is found in various areas of the brain and mediates fast synaptic transmission in the central nervous system (1). Cl-HIBO (chloro-homoibotenic acid) is a subtype selective AMPA receptor agonist (2).

Biological Activity

Subtype-selective and strongly desensitising AMPA receptor agonist; selective for GluR1 and GluR2 subunit-containing receptors (EC 50 values are 4.7, 1.7, 2700 and 1300 μ M for rat recombinant homomeric GluR1, 2, 3 and 4 receptors respectively).

(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID Suppliers

China 15 United Kingdom 1 United States 6 USA 1 Global 23
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
JinOu Biomedical (Nanjing) Co., Ltd.
Tel
13000000000
Fax
jinoupharma@163
Email
jinoupharma@163.com
Country
China
ProdList
11721
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24644
Advantage
58
Nantong QuanYi Biotechnology Co., Ltd
Tel
0513-66337626 18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
4988
Advantage
58
TargetMol Chemicals Inc.
Tel
+8613564774135
Email
zijue.cai@tsbiochem.com
Country
United States
ProdList
19885
Advantage
58
ApexBio Technology
Tel
--
Fax
--
Email
sales@apexbt.com
Country
United States
ProdList
6251
Advantage
58

909400-43-7, (RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACIDRelated Search:


  • 2-AMINO-3-(4-CHLORO-3-HYDROXYISOXAZOL-5-YL)PROPANOIC ACID
  • CL-HIBO
  • (RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID
  • 4-Chlorohomoibotenic acid
  • 5-Isoxazolepropanoic acid, α-amino-4-chloro-2,3-dihydro-3-oxo-
  • ClHIBO,Cl HIBO
  • 909400-43-7