(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID

Product Name
(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID
CAS No.
909400-43-7
Chemical Name
(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID
Synonyms
CL-HIBO;ClHIBO,Cl HIBO;4-Chlorohomoibotenic acid;2-AMINO-3-(4-CHLORO-3-HYDROXYISOXAZOL-5-YL)PROPANOIC ACID;5-Isoxazolepropanoic acid, α-amino-4-chloro-2,3-dihydro-3-oxo-;(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID
CBNumber
CB4691192
Molecular Formula
C6H7ClN2O4
Formula Weight
206.58
MOL File
Mol file
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(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID Property

Density 
1.66±0.1 g/cm3(Predicted)
storage temp. 
Store at RT
pka
2.26±0.10(Predicted)
form 
Powder
Water Solubility 
Soluble to 20 mM in water
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
1673
Product name
Cl-HIBO
Purity
≥99%(HPLC)
Packaging
10
Price
$254
Updated
2021/12/16
Tocris
Product number
1673
Product name
Cl-HIBO
Purity
≥99%(HPLC)
Packaging
50
Price
$1050
Updated
2021/12/16
TRC
Product number
C853703
Product name
Cl-HIBO
Packaging
10mg
Price
$205
Updated
2021/12/16
TRC
Product number
C853703
Product name
Cl-HIBO
Packaging
25mg
Price
$405
Updated
2021/12/16
Usbiological
Product number
255003
Product name
Cl-HIBO
Packaging
10mg
Price
$531
Updated
2021/12/16
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(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID Chemical Properties,Usage,Production

Uses

The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA receptor), a heterotetrameric transmembrane receptor, is found in various areas of the brain and mediates fast synaptic transmission in the central nervous system (1). Cl-HIBO (chloro-homoibotenic acid) is a subtype selective AMPA receptor agonist (2).

Biological Activity

Subtype-selective and strongly desensitising AMPA receptor agonist; selective for GluR1 and GluR2 subunit-containing receptors (EC 50 values are 4.7, 1.7, 2700 and 1300 μ M for rat recombinant homomeric GluR1, 2, 3 and 4 receptors respectively).

(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID Suppliers

China 15 United Kingdom 1 United States 6 USA 1 Global 23
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
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86-21-50328109
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3bsc@sina.com
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China
ProdList
15839
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EMMX Biotechnology LLC
Tel
888-539-0666
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888-539-0666
Email
info@emmx.com
Country
United States
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8447
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TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
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32080
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MedBioPharmaceutical Technology Inc
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021-69568360 18916172912
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order@med-bio.cn
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China
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JinOu Biomedical (Nanjing) Co., Ltd.
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13000000000
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jinoupharma@163
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jinoupharma@163.com
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China
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11721
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TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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China
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24647
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Nantong QuanYi Biotechnology Co., Ltd
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0513-66337626 18051384581
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sales@chemhifuture.com
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China
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4870
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TargetMol Chemicals Inc.
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+8613564774135
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zijue.cai@tsbiochem.com
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United States
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ApexBio Technology
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Email
sales@apexbt.com
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United States
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6251
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909400-43-7, (RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACIDRelated Search:


  • 2-AMINO-3-(4-CHLORO-3-HYDROXYISOXAZOL-5-YL)PROPANOIC ACID
  • CL-HIBO
  • (RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID
  • 4-Chlorohomoibotenic acid
  • 5-Isoxazolepropanoic acid, α-amino-4-chloro-2,3-dihydro-3-oxo-
  • ClHIBO,Cl HIBO
  • 909400-43-7