(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID

Product Name
(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID
CAS No.
909400-43-7
Chemical Name
(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID
Synonyms
CL-HIBO;ClHIBO,Cl HIBO;4-Chlorohomoibotenic acid;2-AMINO-3-(4-CHLORO-3-HYDROXYISOXAZOL-5-YL)PROPANOIC ACID;5-Isoxazolepropanoic acid, α-amino-4-chloro-2,3-dihydro-3-oxo-;(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID
CBNumber
CB4691192
Molecular Formula
C6H7ClN2O4
Formula Weight
206.58
MOL File
Mol file
More
Less

(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID Property

Density 
1.66±0.1 g/cm3(Predicted)
storage temp. 
Store at RT
pka
2.26±0.10(Predicted)
form 
Powder
Water Solubility 
Soluble to 20 mM in water
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Tocris
Product number
1673
Product name
Cl-HIBO
Purity
≥99%(HPLC)
Packaging
10
Price
$254
Updated
2021/12/16
Tocris
Product number
1673
Product name
Cl-HIBO
Purity
≥99%(HPLC)
Packaging
50
Price
$1050
Updated
2021/12/16
TRC
Product number
C853703
Product name
Cl-HIBO
Packaging
10mg
Price
$205
Updated
2021/12/16
TRC
Product number
C853703
Product name
Cl-HIBO
Packaging
25mg
Price
$405
Updated
2021/12/16
Usbiological
Product number
255003
Product name
Cl-HIBO
Packaging
10mg
Price
$531
Updated
2021/12/16
More
Less

(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID Chemical Properties,Usage,Production

Uses

The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA receptor), a heterotetrameric transmembrane receptor, is found in various areas of the brain and mediates fast synaptic transmission in the central nervous system (1). Cl-HIBO (chloro-homoibotenic acid) is a subtype selective AMPA receptor agonist (2).

Biological Activity

Subtype-selective and strongly desensitising AMPA receptor agonist; selective for GluR1 and GluR2 subunit-containing receptors (EC 50 values are 4.7, 1.7, 2700 and 1300 μ M for rat recombinant homomeric GluR1, 2, 3 and 4 receptors respectively).

(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID Suppliers

China 15 United Kingdom 1 United States 6 USA 1 Global 23
Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77

909400-43-7, (RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACIDRelated Search:


  • 2-AMINO-3-(4-CHLORO-3-HYDROXYISOXAZOL-5-YL)PROPANOIC ACID
  • CL-HIBO
  • (RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID
  • 4-Chlorohomoibotenic acid
  • 5-Isoxazolepropanoic acid, α-amino-4-chloro-2,3-dihydro-3-oxo-
  • ClHIBO,Cl HIBO
  • 909400-43-7