4-Chloro-6-hydrazinopyrimidine

Product Name: 4-Chloro-6-hydrazinopyrimidine
CAS No.: 5767-35-1
Chemical Name: 4-Chloro-6-hydrazinopyrimidine
Synonyms: 6-chloro-4-hydrazinopyrimidine;4-CHLORO-6-HYDRAZINOPYRIMIDINE;4-chloro-6-hydrazinylpyriMidine;4-chloro-6-aziridinylpyrimidine;(6-chloro-4-pyrimidinyl)hydrazine;(6-chloropyrimidin-4-yl)hydrazine;Pyrimidine, 4-chloro-6-hydrazinyl-;4-Chloro-6-hydrazinopyriMidine, 95+%;4(1H)-Pyrimidinone, 6-chloro-, hydrazone;4(1H)-Pyrimidinone, 6-chloro-, hydrazone (9CI)
CBNumber: CB4705208
Molecular Formula: C4H5ClN4
Formula Weight: 144.56
MOL File: 5767-35-1.mol

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4-Chloro-6-hydrazinopyrimidine Property

Melting point:: 164-165 °C
Boiling point:: 254.8±50.0 °C(Predicted)
Density: 1.63±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka: 7.29±0.70(Predicted)
Appearance: White to off-white Solid
CAS DataBase Reference: 5767-35-1(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

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N-Bromosuccinimide Price

TRC

Product number: C349415
Product name: 4-Chloro-6-hydrazinopyrimidine
Packaging: 250mg
Price: $55
Updated: 2021/12/16

TRC

Product number: C349415
Product name: 4-Chloro-6-hydrazinopyrimidine
Packaging: 1g
Price: $75
Updated: 2021/12/16

Ark Pharm

Product number: AK-23764
Product name: 4-Chloro-6-hydrazinopyrimidine
Purity: 98%
Packaging: 250mg
Price: $12
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC149781
Product name: 4-Chloro-6-hydrazinopyrimidine
Packaging: 250mg
Price: $50
Updated: 2021/12/16

AK Scientific

Product number: J54594
Product name: 4-Chloro-6-hydrazinopyrimidine
Packaging: 1g
Price: $60
Updated: 2021/12/16

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4-Chloro-6-hydrazinopyrimidine Chemical Properties,Usage,Production

Synthesis

1193-21-1

5767-35-1

General procedure for the synthesis of 4-chloro-6-hydrazinopyrimidines from 4,6-dichloropyrimidines: 4,6-dichloropyrimidines (15 g, 100 mmol) were dissolved in ethanol in a 250 mL three-necked flask and cooled to 0-5 °C. Hydrazine hydrate (4.7 mL, 120 mmol) was slowly added dropwise to the reaction flask under cooling conditions. After the dropwise addition, the reaction mixture was stirred at room temperature for 90 minutes. The reaction progress was monitored by thin layer chromatography (TLC). After completion of the reaction, the mixture was poured into water and the crude product was precipitated. Purification by ethanol recrystallization gave 4-chloro-6-hydrazinopyrimidine (A) as a light yellow solid. The yield was 95%; the product was a pale yellowish-white solid; the Rf value was 0.5 (unfolding agent: hexane/ethyl acetate, 4:1); the melting point was 164 °C. 1H NMR (DMSO-d6, 400 MHz) δ= 8.83 (s, 1H), 8.17 (s, 1H), 6.76 (s, 1H), 4.50 (s, 2H); EI-MS (m/z): 145.02 (M + 1).

References

[1] Journal of Molecular Structure, 2019, vol. 1175, p. 551 - 565
[2] Chemical Biology and Drug Design, 2018, vol. 92, # 3, p. 1683 - 1691
[3] Patent: WO2008/42639, 2008, A1. Location in patent: Page/Page column 81
[4] Patent: WO2008/42639, 2008, A1. Location in patent: Page/Page column 81
[5] Synlett, 2010, # 14, p. 2179 - 2183

4-Chloro-6-hydrazinopyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Chloro-6-hydrazinopyrimidine Suppliers

China 95 Europe 1 France 1 Germany 2 India 1 The Netherlands 1 Ukraine 2 United Kingdom 5 United States 16 Global 124

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View Lastest Price from 4-Chloro-6-hydrazinopyrimidine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 4-Chloro-6-hydrazinopyriMidine 5767-35-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2020-05-14

Career Henan Chemical Co

Product: 4-Chloro-6-hydrazinopyrimidine 5767-35-1
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 10000KGS
Release date: 2020-01-09

5767-35-1, 4-Chloro-6-hydrazinopyrimidineRelated Search:

Carbobenzoxyhydrazide Silver sulfadiazine Sulfadiazine CHLORODIMETHYLVINYLSILANE Uracil Chloromethyl chlorosulfate Cytosine tert-Butyl carbazate 4-Chloropyrimidine Difluorochloromethane 4-CHLORO-6-HYDRAZINO-PYRIMIDIN-5-YLAMINE 2-Chloro-4-hydrazinopyrimidine ,98%,2-CHLORO-4-HYDRAZINOPYRIMIDINE 4-Chloro-6-hydrazino-2-(methylthio)pyrimidine 4-Chloro-6-hydrazinopyrimidine N-(4-CHLORO-6-HYDRAZINO-5-PHENYLPYRIMIDIN-2-YL)-N,N-DIMETHYLAMINE BENZENECARBALDEHYDE N-[6-CHLORO-2-(METHYLSULFANYL)-4-PYRIMIDINYL]HYDRAZONE 2-[6-CHLORO-2-(METHYLSULFANYL)-4-PYRIMIDINYL]-N-PHENYL-1-HYDRAZINECARBOXAMIDE 5-chloro-2-hydrazinopyrimidine-4-carboxylic acid

4-CHLORO-6-HYDRAZINOPYRIMIDINE

4(1H)-Pyrimidinone, 6-chloro-, hydrazone (9CI)

(6-chloropyrimidin-4-yl)hydrazine

(6-chloro-4-pyrimidinyl)hydrazine

6-chloro-4-hydrazinopyrimidine

4-chloro-6-hydrazinylpyriMidine

4-Chloro-6-hydrazinopyriMidine, 95+%

4(1H)-Pyrimidinone, 6-chloro-, hydrazone

Pyrimidine, 4-chloro-6-hydrazinyl-

4-chloro-6-aziridinylpyrimidine

5767-35-1

Heterocycle-Pyrimidine series

PYRIMIDINE