H-(2S,4R)-GAMMA-HYDROXY-GLU-OH

Product Name: H-(2S,4R)-GAMMA-HYDROXY-GLU-OH
CAS No.: 2485-33-8
Chemical Name: H-(2S,4R)-GAMMA-HYDROXY-GLU-OH
Synonyms: H-(2S,4R)-Glu(g-OH)-OH;H-(2S,4R)-g-Hydroxy-Glu-OH;H-(2S,4R)-GLU(GAMMA-OH)-OH;H-(2S,4R)-γ-Hydroxy-Glu-OH;H-(2S,4R)-GAMMA-HYDROXY-GLU-OH;(4R)-4-Hydroxy-L-glutaMic Acid;erythro-4-Hydroxy-L-glutaMic Acid;(2S,4R)-4-Hydroxy-L-glutaMic Acid;(2S,4R)-γ-Hydroxy-L-glutamic acid;L-Glutamic acid, 4-hydroxy-, (4R)-
CBNumber: CB4706816
Molecular Formula: C5H9NO5
Formula Weight: 163.13
MOL File: 2485-33-8.mol

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H-(2S,4R)-GAMMA-HYDROXY-GLU-OH Property

Melting point:: >159°C (dec.)
Boiling point:: 458.7±45.0 °C(Predicted)
Density: 1.595±0.06 g/cm3(Predicted)
storage temp.: -15°C
solubility: DMSO (Slightly), Water (Slightly)
pka: 2.15±0.10(Predicted)
form: Solid
color: White to Off-White
optical activity: [α]/D 20.5±1.5°, c = 1 in H2O
BRN: 1725871
Stability:: Hygroscopic
InChI: 1S/C5H9NO5/c6-2(4(8)9)1-3(7)5(10)11/h2-3,7H,1,6H2,(H,8,9)(H,10,11)/t2-,3+/m0/s1
InChIKey: HBDWQSHEVMSFGY-STHAYSLISA-N
SMILES: N[C@@H](C[C@@H](O)C(O)=O)C(O)=O

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Safety

WGK Germany: 3
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 76157
Product name: (4R)-4-Hydroxy-L-glutamic acid
Purity: ≥98.0% (TLC)
Packaging: 10mg
Price: $260
Updated: 2025/07/31

Sigma-Aldrich

Product number: 76157
Product name: (4R)-4-Hydroxy-L-glutamic acid
Purity: ≥98.0% (TLC)
Packaging: 50mg
Price: $318.5
Updated: 2025/07/31

TRC

Product number: H942550
Product name: (2S,4R)-4-Hydroxy-L-glutamicAcid
Packaging: 10mg
Price: $165
Updated: 2021/12/16

Chem-Impex

Product number: 07066
Product name: (2,4)-γ-Hydroxy-L-glutamic acid
Purity: ≥ 98% (TLC)
Packaging: 25MG
Price: $166
Updated: 2021/12/16

Chem-Impex

Product number: 07066
Product name: (2S,4R)-γ-Hydroxy-L-glutamicacid,≥98%(TLC)
Purity: ≥98%(TLC)
Packaging: 1G
Price: $1615.58
Updated: 2021/12/16

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H-(2S,4R)-GAMMA-HYDROXY-GLU-OH Chemical Properties,Usage,Production

Uses

(2S,4R)-4-Hydroxy-L-glutamic Acid is a metabolite of Glutamic acid (G596960).

Definition

ChEBI: Erythro-4-hydroxy-L-glutamic acid is a 4-hydroxy-L-glutamic acid. It has a role as a Saccharomyces cerevisiae metabolite. It is functionally related to a L-glutamic acid. It is a conjugate acid of an erythro-4-hydroxy-L-glutamate(1-).

Biological Activity

(4R)-4-Hydroxy-L-glutamic acid or (2S,4R)-4-hydroxyglutamate was shown to activate the metabotropic glutamate receptors, mGlu1a, mGlu2, and mGlu8a in a dose-dependent manner. ', 'Substrate for aminotransferase; pharmacological characterization at human glutamate transporter subtypes 1-3; for studying structure-activity relationships (SAR) for ionotropic and metabotropic glutamate receptors.

IC 50

Human Endogenous Metabolite

H-(2S,4R)-GAMMA-HYDROXY-GLU-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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H-(2S,4R)-GAMMA-HYDROXY-GLU-OH Suppliers

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2485-33-8