4-BROMO-2-(BROMOMETHYL)-1-METHOXYBENZENE
- Product Name
- 4-BROMO-2-(BROMOMETHYL)-1-METHOXYBENZENE
- CAS No.
- 184970-28-3
- Chemical Name
- 4-BROMO-2-(BROMOMETHYL)-1-METHOXYBENZENE
- Synonyms
- 4-Bromo-2-bromomethylanisole;4-bromo-2-(bromomethyl)-1-methoxybenze;4-BROMO-2-(BROMOMETHYL)-1-METHOXYBENZENE;Benzene, 4-bromo-2-(bromomethyl)-1-methoxy-
- CBNumber
- CB4714198
- Molecular Formula
- C8H8Br2O
- Formula Weight
- 279.96
- MOL File
- 184970-28-3.mol
4-BROMO-2-(BROMOMETHYL)-1-METHOXYBENZENE Property
- storage temp.
- Inert atmosphere,Room Temperature
- Appearance
- White to yellow Solid
Safety
- HS Code
- 2909309090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B680733
- Product name
- 4-Bromo-2-(bromomethyl)-1-methoxybenzene
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- V3954
- Product name
- 4-Bromo-2-(bromomethyl)-1-methoxybenzene
- Packaging
- 250mg
- Price
- $131
- Updated
- 2021/12/16
- Product number
- 2707-9-18
- Product name
- 5-Bromo-2-methoxybenzyl bromide
- Packaging
- 1g
- Price
- $276
- Updated
- 2021/12/16
- Product number
- 175828
- Product name
- 4-Bromo-2-(bromomethyl)-1-methoxybenzene
- Packaging
- 1g
- Price
- $540
- Updated
- 2021/12/16
- Product number
- HCH0044032
- Product name
- 4-BROMO-2-(BROMOMETHYL)-1-METHOXYBENZENE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $794.34
- Updated
- 2021/12/16
4-BROMO-2-(BROMOMETHYL)-1-METHOXYBENZENE Chemical Properties,Usage,Production
Synthesis
80866-82-6
184970-28-3
General procedure for the synthesis of 4-bromo-2-(bromomethyl)-1-methoxybenzene from 5-bromo-2-methoxybenzyl alcohol: (5-bromo-2-methoxyphenyl)methanol (1.0 g, 4.6 mmol) was dissolved in dichloromethane (10 mL) at 0 °C and tribromophosphine (1 M solution in dichloromethane, 9.2 mL, 9.2 mmol) was slowly added. After removing the ice bath, the reaction mixture was stirred at room temperature for 15 minutes. After completion of the reaction, the reaction solution was concentrated under reduced pressure and the residue was poured into cold saturated sodium bicarbonate solution and the organic phase was extracted with pentane. The organic phase was dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to afford 4-bromo-2-(bromomethyl)-1-methoxybenzene (1.15 g, 89% yield) as a white crystalline solid. The product was characterized by 1H NMR (500 MHz, CDCl3) and 13C NMR (126 MHz, CDCl3) with the following data: 1H NMR δ 7.44 (d, J = 2.5 Hz, 1H), 7.38 (dd, J = 8.9, 6.1 Hz, 1H), 4.47 (s, 2H), 3.87 (s, 3H); 13C NMR δ 156.7, 133.6, 132.8, 128.4, 112.8, 112.7, 56.0, 27.5.
References
[1] Patent: US2007/249607, 2007, A1. Location in patent: Page/Page column 73
[2] Tetrahedron Letters, 2011, vol. 52, # 20, p. 2554 - 2556
4-BROMO-2-(BROMOMETHYL)-1-METHOXYBENZENE Preparation Products And Raw materials
Raw materials
Preparation Products
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