ChemicalBook > CAS DataBase List > 3,5-DIFLUORO-2-NITROBENZOIC ACID

3,5-DIFLUORO-2-NITROBENZOIC ACID

Product Name: 3,5-DIFLUORO-2-NITROBENZOIC ACID
CAS No.: 331765-71-0
Chemical Name: 3,5-DIFLUORO-2-NITROBENZOIC ACID
Synonyms: BUTTPARK 51\07-01;3,5-DIFLUORO-2-NITROBENZOIC ACID;2-Carboxy-4,6-difluoronitrobenzene;Benzoic acid, 3,5-difluoro-2-nitro-
CBNumber: CB4720340
Molecular Formula: C7H3F2NO4
Formula Weight: 203.1
MOL File: Mol file

Less

3,5-DIFLUORO-2-NITROBENZOIC ACID Property

storage temp.: Sealed in dry,Room Temperature
form: powder
color: Lumpy, off white to beige

Less

Safety

Hazard Codes: Xi
Hazard Note: Irritant
HS Code: 2916399090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

Less

N-Bromosuccinimide Price

TRC

Product number: D458370
Product name: 3,5-Difluoro-2-nitrobenzoicAcid
Packaging: 50mg
Price: $45
Updated: 2021/12/16

TRC

Product number: D458370
Product name: 3,5-Difluoro-2-nitrobenzoicAcid
Packaging: 100mg
Price: $65
Updated: 2021/12/16

TRC

Product number: D458370
Product name: 3,5-Difluoro-2-nitrobenzoicAcid
Packaging: 500mg
Price: $240
Updated: 2021/12/16

Apolloscientific

Product number: PC0922
Product name: 3,5-Difluoro-2-nitrobenzoicacid
Packaging: 25g
Price: $348
Updated: 2021/12/16

AK Scientific

Product number: 3811AB
Product name: 3,5-Difluoro-2-nitrobenzoicacid
Packaging: 5g
Price: $371
Updated: 2021/12/16

Less

3,5-DIFLUORO-2-NITROBENZOIC ACID Chemical Properties,Usage,Production

Synthesis

455-40-3

331765-71-0

Step 1: 3,5-difluorobenzoic acid (80 g, 506 mmol) was stirred with concentrated sulfuric acid (250 mL) for 1 hour at room temperature. Subsequently, concentrated nitric acid (90 mL) was added slowly and dropwise while the reaction temperature was controlled below 45 °C by a water bath. The reaction mixture was stirred overnight at room temperature. The reaction was quenched by slowly pouring the reaction solution into crushed ice, the precipitated solid was collected by filtration and washed thoroughly with cold water to afford 3,5-difluoro-2-nitrobenzoic acid (compound 273) as a white solid (93.0 g, 91% yield). The product could be used directly in the subsequent reaction without further purification.1H NMR (400 MHz, DMSO-d6) δ 8.01 (ddd, J = 10.9, 8.5, 2.8 Hz, 1H), 7.71 (dt, J = 8.4, 2.2 Hz, 1H).

References

[1] Patent: WO2013/132376, 2013, A1. Location in patent: Page/Page column 234
[2] Patent: EP1214299, 2004, B1. Location in patent: Page 18
[3] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 7, p. 2733 - 2743

3,5-DIFLUORO-2-NITROBENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

Less

3,5-DIFLUORO-2-NITROBENZOIC ACID Suppliers

China 55 France 1 India 1 Italy 1 United Kingdom 4 United States 6 Global 68

Shanghai Harvest Chemical Industrial Co., Ltd.

Tel: 021-31038972,31038973 17321035817
Fax: +86-21-51385350
Email: sales@harvest-chem.com
Country: China
ProdList: 2816
Advantage: 64

SynAsst Chemical.

Tel: 021-60343070
Fax: 021-35122006
Country: China
ProdList: 12740
Advantage: 55

Chengdu Firster Pharmaceutical Co., Ltd.

Tel: 028-87078428 028-87074958
Fax: 8772-8116
Email: chengzhenyong@cdfirster.com
Country: China
ProdList: 2598
Advantage: 60

Xinyanhe Pharmatech Co.,Ltd

Tel: 0519-85252752 15366845260
Fax: 86-0519-85683352
Email: taihuaren@vip.163.com
Country: China
ProdList: 1132
Advantage: 58

JW & Y Pharmlab Co., Ltd.

Tel: 021-64340559 13651849907;
Fax: 021- 64345308
Email: xinyu_shi@jwypharmlab.com.cn
Country: China
ProdList: 12000
Advantage: 58

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7991
Advantage: 55

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 0512-0512-52358471 17715136450
Fax: 05125235 6881
Email: sales@shiyabiopharm.com
Country: China
ProdList: 12127
Advantage: 58

Quzhou AMK BioTech Co., Ltd

Tel: 0570-3081766 18357083060
Fax: 0570-3072337
Email: sales@qzamkbio.com
Country: China
ProdList: 1046
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai CR Corporation Limited

Tel: 13062833949; 4006653949 4006653949
Fax: QQ: 2136646215
Email: fred.wen@crcorporation.cn
Country: China
ProdList: 9757
Advantage: 58

Nanjing LuoDa Chemical Co., Ltd

Tel: 025-66016961 13382082786
Fax: 025-52204547
Country: China
ProdList: 222
Advantage: 55

Aikon International Limited

Tel: 025-66061636 18013972705
Fax: (3)02557626880
Email: qqyang@aikonchem.com
Country: China
ProdList: 15814
Advantage: 58

SHANGHAI FDC-CHEMICAL CO.,LTD

Tel: 021-61469567 13482353728
Fax: 021-61161605
Email: sales@fdc-chemical.com
Country: China
ProdList: 9713
Advantage: 58

Rhawn Reagent

Tel: 400-400-1332688 18019345275
Fax: 400-133-2688
Email: amy@rhawn.cn
Country: China
ProdList: 14948
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Suzhou Xiya Pharmaceutical Co., Ltd.

Tel: 0512-87819718 18912655635
Email: 2587879032@qq.com
Country: China
ProdList: 1401
Advantage: 58

DILICHEM

Tel: 0519-0519-81238123 18014346496
Email: shichaojun@126.com
Country: China
ProdList: 394
Advantage: 58

Henan's chemical products co., LTD

Tel: 0371-60919097 15378766539
Fax: 0371-60919097
Email: 794449696@qq.com
Country: China
ProdList: 4996
Advantage: 58

Shanghai SPAR pharmaceutical technology co., LTD

Tel: 021-000000 13917643586;
Email: admin@jingshipharmatech.com
Country: China
ProdList: 9857
Advantage: 58

Cool Pharm, Ltd

Tel: 021-58581007 18019463053
Fax: 021-50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12878
Advantage: 58

Nanjing Qishi Biotechnology Co. Ltd.

Tel: 19822610310
Email: 3122922726@qq.com
Country: China
ProdList: 114
Advantage: 58

Chengdu Forest Science and Technology Development Co,. Ltd

Tel: 028-87925786 18010564218
Fax: 028-61777050
Email: vendi@cdforestchem.com
Country: China
ProdList: 1992
Advantage: 58

Shanghai zhigan biotechnology co., LTD

Tel
Email: zhiqianbio@126.com
Country: China
ProdList: 19778
Advantage: 58

Allfluoro pharmaceutical co. ltd.

Tel: +86-400-0216110 +86-15958047586
Fax: 0086-21-33275002
Email: sales@allfluoro.com
Country: China
ProdList: 11385
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418684 +8618949823763
Fax: 0086-551-65418684
Email: sales@tnjchem.com
Country: China
ProdList: 25356
Advantage: 58

Labnetwork lnc.

Tel: +86-27-50766799 +8618062016861
Email: contact@labnetwork.com
Country: China
ProdList: 19987
Advantage: 58

Win-Win chemical CO., Limited

Tel: +86-0086-577-64498589 +86-15355981851
Fax: 0086-577-56994596
Email: sales@win-winchemical.com
Country: China
ProdList: 14359
Advantage: 58

Nanjing Ze Feng biological medicine technology Co., Ltd.

Tel: 18851912129 18851912129;
Email: 1670471576@qq.com
Country: China
ProdList: 800
Advantage: 58

Shanghai Amico Chemicals Co. LTD

Tel: 微信 17321281695 18019252918
Fax: qq:1454668768
Email: 1454668768@qq.com
Country: China
ProdList: 14856
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

Fuxin Pharmaceutical

Tel: +86-021-021-50872116 +8613122107989
Email: contact@fuxinpharm.com
Country: China
ProdList: 10000
Advantage: 58

Wuhan ShuEr Biology Technology Co.,Ltd

Tel: 027-15827133616-6 15827133616
Fax: QQ 1799696397
Email: 1799696397@qq.com
Country: China
ProdList: 2582
Advantage: 58

Nanjing Puxin Pharmaceutical Technology Co., Ltd

Tel: 17366295326
Fax: QQ360829978
Email: puxinpharma_2017@126.com
Country: China
ProdList: 2444
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Shanghai UCHEM Inc.

Tel: 18939844854
Fax: QQ3004479448
Email: sales6@myuchem.com
Country: China
ProdList: 4997
Advantage: 58

Beijing Stronger Science Co., Ltd.

Tel: 0531-88924771 15614660963
Email: elsa.hang@strongerscience.com
Country: China
ProdList: 10623
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 59936
Advantage: 58

Qi Qi hang Biotechnology Co., Ltd.

Tel: 15870833005
Email: 2232044025@qq.com
Country: China
ProdList: 8206
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Jiaxing Zhejia Biotechnology Co., LTD

Tel: 0573-85609002 18367600069;
Email: zhejia01@163.com
Country: China
ProdList: 8886
Advantage: 58

Dongyang Qiusuo Medical Technology Co., LTD

Tel: 17502510579
Email: 2785299132@qq.com
Country: China
ProdList: 1558
Advantage: 58

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 18621169109
Email: market03@meryer.com
Country: China
ProdList: 27987
Advantage: 58

Shandong Bourne Pharmaceutical Co. , Ltd.

Tel: 15865694623
Email: 1825792389@qq.com
Country: China
ProdList: 370
Advantage: 58

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Email: syeu@accelachem.com
Country: China
ProdList: 11015
Advantage: 58

Changzhou Yanji Biotechnology Co., Ltd.

Tel: 0519-83556355 18015005120
Fax: -
Email: shikewei397@163.com
Country: China
ProdList: 3734
Advantage: 55

nanjing

Tel: 13376082704 13376084917;
Email: 3930959291@qq.com
Country: China
ProdList: 2080
Advantage: 58

Shanghai Ken chemical Technology Co.,ltd

Tel: 02152215958
Email: 47697177@qq.com
Country: China
ProdList: 10011
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Zhengzhou Haochuang New Material Co., Ltd.

Tel: 19139721821
Email: 3545426645@qq.com
Country: China
ProdList: 4989
Advantage: 58

331765-71-0, 3,5-DIFLUORO-2-NITROBENZOIC ACIDRelated Search:

3,5-DIFLUORO-2-NITROBENZOIC ACID

BUTTPARK 51\07-01

2-Carboxy-4,6-difluoronitrobenzene

Benzoic acid, 3,5-difluoro-2-nitro-

331765-71-0