3-MATIDA
- Product Name
- 3-MATIDA
- CAS No.
- 518357-51-2
- Chemical Name
- 3-MATIDA
- Synonyms
- 3-MATIDA;3 MATIDA,3MATIDA;α-Amino-5-carboxy-3-methyl-2-thiopheneaceticacid;2-Thiopheneacetic acid, α-amino-5-carboxy-3-methyl-;ALPHA-AMINO-5-CARBOXY-3-METHYL-2-THIOPHENEACETIC ACID;5-[amino(carboxy)methyl]-4-methylthiophene-2-carboxylic acid
- CBNumber
- CB4723497
- Molecular Formula
- C8H9NO4S
- Formula Weight
- 215.23
- MOL File
- 518357-51-2.mol
3-MATIDA Property
- storage temp.
- Store at +4°C
- solubility
- Soluble to 100 mM in 1eq. NaOH and to 50 mM in DMSO
- form
- Powder
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 254392
- Product name
- 3-MATIDA
- Packaging
- 10mg
- Price
- $480
- Updated
- 2021/12/16
- Product number
- M198105
- Product name
- 3-MATIDA
- Packaging
- 2.5mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- B6969
- Product name
- 3-MATIDA
- Packaging
- 10mg
- Price
- $322
- Updated
- 2021/12/16
- Product number
- AAA0003182
- Product name
- 3-MATIDA
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $721.59
- Updated
- 2021/12/16
- Product number
- AAA0003182
- Product name
- 3-MATIDA
- Purity
- 95.00%
- Packaging
- 50MG
- Price
- $1327.97
- Updated
- 2021/12/16
3-MATIDA Chemical Properties,Usage,Production
Uses
3-MATIDA is a potent mGluR-1 antagonist.
Definition
ChEBI: 5-[amino(carboxy)methyl]-4-methyl-2-thiophenecarboxylic acid is an alpha-amino acid.
Biological Activity
Potent metabotropic glutamate mGlu 1 receptor antagonist (IC 50 = 6.3 μ M at rat mGlu 1a ). Displays ≥ 40-fold selectivity over other receptors: mGlu 5 , mGlu 2 , mGlu 4a (IC 50 > 300 μ M), NMDA and AMPA (IC 50 = 250 μ M). Neuroprotective in cultured murine cortical cells and rat hippocampal slice cultures in vitro . Reduces the volume of ischemia-induced brain infarcts in rats following systemic administration in vivo .