BISINDOLYLMALEIMIDE III
- Product Name
- BISINDOLYLMALEIMIDE III
- CAS No.
- 137592-43-9
- Chemical Name
- BISINDOLYLMALEIMIDE III
- Synonyms
- BISINDOLYLMALEIMIDE III;Bisindolylmaleimide III, PKC inhibitor;3-[1-(3-aminopropyl)indol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione;3-(1-(3-Aminopropyl)-1H-indol-3-yl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-yl)-
- CBNumber
- CB4728487
- Molecular Formula
- C23H20N4O2
- Formula Weight
- 384.43
- MOL File
- Mol file
BISINDOLYLMALEIMIDE III Property
- Boiling point:
- 708.7±60.0 °C(Predicted)
- Density
- 1.41±0.1 g/cm3(Predicted)
- solubility
- DMSO: soluble; Methanol: soluble
- form
- A crystalline solid
- pka
- 8.15±0.60(Predicted)
- color
- Brown to reddish brown
N-Bromosuccinimide Price
- Product number
- 11072
- Product name
- Bisindolylmaleimide III
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $57
- Updated
- 2024/03/01
- Product number
- 11072
- Product name
- Bisindolylmaleimide III
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $172
- Updated
- 2024/03/01
- Product number
- 044604
- Product name
- Bisindolylmaleimide III
- Packaging
- 1mg
- Price
- $295
- Updated
- 2021/12/16
- Product number
- 162899
- Product name
- Bisindolylmaleimide III
- Packaging
- 5mg
- Price
- $425
- Updated
- 2021/12/16
- Product number
- 0282CA
- Product name
- 3-[1-(3-Aminopropyl)-1H-indol-3-YL]-4-(1H-indol-3-YL)-1H-pyrrole-2,5-dione
- Packaging
- 5mg
- Price
- $289
- Updated
- 2021/12/16
BISINDOLYLMALEIMIDE III Chemical Properties,Usage,Production
Description
Bisindolylmaleimide III was developed as a protein kinase C (PKC) inhibitor with structural similarity to the nonspecific PKC inhibitor staurosporine. At 1 μM, bisindolylmaleimide III inhibits 93% of PKCα kinase activity and also inhibits many other protein kinases including, S6K1, MAPKAP-
Uses
Bisindolylmaleimide III is a protein kinase C inhibitor and was also shown to exhibit inhibitory activities towards PDK1, an important kinase in the insulin signaling pathway,
Definition
ChEBI: Bisindolylmaleimide III is a member of maleimides and a member of indoles. It has a role as an EC 2.7.11.13 (protein kinase C) inhibitor. It is functionally related to a maleimide.
BISINDOLYLMALEIMIDE III Preparation Products And Raw materials
Raw materials
Preparation Products
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