ChemicalBook > CAS DataBase List > ALPHA-CORTOLONE

ALPHA-CORTOLONE

Product Name
ALPHA-CORTOLONE
CAS No.
516-42-7
Chemical Name
ALPHA-CORTOLONE
Synonyms
CORTOLONE;α-Cortolone;α-Cortolone-d5;ALPHA-CORTOLONE;Alpha Cortolone D5;A-cortolone crystalline;5β-Pregnane-3α,17α,20α,21-tetrol-11-one;5β-Pregnan-3α, 17, 20α, 21-Tetrol-11-One;3α,17α,20α,21-Tetrahydroxy-5β-pregnan-11-one;(20S)-3α,17,20,21-Tetrahydroxy-5β-pregnan-11-one
CBNumber
CB4729833
Molecular Formula
C21H34O5
Formula Weight
366.49
MOL File
516-42-7.mol
More
Less

ALPHA-CORTOLONE Property

Melting point:
208-209°
alpha 
D25 +44° (c = 0.5 in ethanol); D28 +34.2° (ethanol)
Boiling point:
564.1±50.0 °C(Predicted)
Density 
1.248±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
pka
13.95±0.70(Predicted)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Medical Isotopes, Inc.
Product number
63782
Product name
α-Cortolone
Packaging
10mg
Price
$490
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
SHG0001792
Product name
ALPHA-CORTOLONE
Purity
98.00%
Packaging
50MG
Price
$750.75
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
SHG0001792
Product name
ALPHA-CORTOLONE
Purity
98.00%
Packaging
0.1G
Price
$1444.3
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
SHG0001792
Product name
ALPHA-CORTOLONE
Purity
98.00%
Packaging
500MG
Price
$1963.5
Updated
2021/12/16
AHH
Product number
MT-06835
Product name
alpha-Cortolone
Purity
98%
Packaging
0.1g
Price
$600
Updated
2021/12/16
More
Less

ALPHA-CORTOLONE Chemical Properties,Usage,Production

Uses

α-Cortolone is a human urinary metabolite of Cortisol ((H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.

Definition

ChEBI: Cortolone is a 21-hydroxy steroid.

ALPHA-CORTOLONE Preparation Products And Raw materials

Raw materials

Preparation Products

516-42-7, ALPHA-CORTOLONERelated Search:


  • 3-ALPHA,17-ALPHA,20-ALPHA,21-TETRAHYDROXY-5-BETA-PREGNAN-11-ONE
  • A-cortolone crystalline
  • CORTOLONE
  • ALPHA-CORTOLONE
  • 5-BETA-PREGNAN-3-ALPHA, 17,20-ALPHA, 21-TETROL-11-ONE
  • 5BETA-PREGNAN-3ALPHA,17ALPHA,20ALPHA,21-TETROL-11-ONE
  • (3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1S)-1,2-dihydroxyethyl]-3,17-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one
  • (20S)-3α,17,20,21-Tetrahydroxy-5β-pregnan-11-one
  • 3α,17α,20α,21-Tetrahydroxy-5β-pregnan-11-one
  • 5β-Pregnane-3α,17α,20α,21-tetrol-11-one
  • α-Cortolone
  • α-Cortolone-d5
  • Alpha Cortolone D5
  • 5β-Pregnan-3α, 17, 20α, 21-Tetrol-11-One
  • Pregnan-11-one, 3,17,20,21-tetrahydroxy-, (3α,5β,20S)-
  • 516-42-7