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(R)-3-Aminopyrrolidine

Product Name
(R)-3-Aminopyrrolidine
CAS No.
116183-82-5
Chemical Name
(R)-3-Aminopyrrolidine
Synonyms
R-AP;MYP23;alpha-2-MRAP;CAS:116183-82-5;3-amino-R-pyrrolidine;(R)-pyrrolidin-3-amine;(R)-3-AMINOPYRROLIDINE;(3R)-3-Pyrrolidinamine;(3R)-pyrrolidin-3-aMine;(3R)-Pyrrolidine-3-amine
CBNumber
CB4730772
Molecular Formula
C4H10N2
Formula Weight
86.14
MOL File
116183-82-5.mol
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(R)-3-Aminopyrrolidine Property

Boiling point:
164-165 °C(lit.)
Density 
0.984 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.489(lit.)
Flash point:
147 °F
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
clear liquid
pka
9.94±0.20(Predicted)
color 
Colorless to Almost colorless
optical activity
[α]/D +20°, neat
CAS DataBase Reference
116183-82-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
NA 1993 / PGIII
WGK Germany 
3
HazardClass 
8
PackingGroup 
III
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
540781
Product name
(R)-(+)-3-Aminopyrrolidine
Purity
98%
Packaging
1g
Price
$123
Updated
2025/07/31
TCI Chemical
Product number
A1167
Product name
(3R)-(+)-3-Aminopyrrolidine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$288
Updated
2025/07/31
TCI Chemical
Product number
A1167
Product name
(3R)-(+)-3-Aminopyrrolidine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$862
Updated
2024/03/01
TCI Chemical
Product number
A1167
Product name
(3R)-(+)-3-Aminopyrrolidine
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$96
Updated
2025/07/31
TRC
Product number
P999183
Product name
(R)-Pyrrolidin-3-amine
Packaging
100mg
Price
$60
Updated
2021/12/16
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(R)-3-Aminopyrrolidine Chemical Properties,Usage,Production

Synthesis

114715-38-7

79286-79-6

General procedure for the synthesis of (S)-3-aminopyrrolidine from (S)-1-benzyl-3-aminopyrrolidine: 7.0 g of (S)-1-benzyl-3-aminopyrrolidine, 25 mL of methanol, and 0.7 g of 5% Pd/C catalyst were added to a 100 mL autoclave. The hydrogen pressure was adjusted to 1 MPa, the temperature was raised to 70 °C and the reaction was kept stirring for 8 hours. Upon completion of the reaction, it was cooled to room temperature and the pressure was slowly released. The reaction mixture was filtered to remove the catalyst and the mother liquor was concentrated and purified by distillation to collect the 80-83 °C/40 kPa fraction to give 3.2 g of (S)-3-aminopyrrolidine. The product was analyzed with 99% chemical purity and 90% optical purity e.e.

References

[1] Patent: US6348600, 2002, B1. Location in patent: Page column 14
[2] Patent: EP1640364, 2006, A1. Location in patent: Page/Page column 10
[3] Patent: EP1236716, 2002, A1. Location in patent: Example 6

(R)-3-Aminopyrrolidine Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-3-Aminopyrrolidine Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
Kaneka Corporation
Tel
--
Fax
--
Email
finechem@kaneka.co.jp
Country
Japan
ProdList
112
Advantage
81
Toray Fine Chemicals Co., Ltd.
Tel
--
Fax
--
Country
Japan
ProdList
143
Advantage
67
Koei Chemical Company, Ltd.
Tel
--
Fax
--
Country
Japan
ProdList
497
Advantage
65
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View Lastest Price from (R)-3-Aminopyrrolidine manufacturers

Career Henan Chemical Co
Product
(R)-3-Aminopyrrolidine 116183-82-5
Price
US $1.00/KG
Min. Order
1KG
Purity
96%
Supply Ability
500kg
Release date
2018-08-20
Career Henan Chemical Co
Product
(R)-3-Aminopyrrolidine 116183-82-5
Price
US $1.00/KG
Min. Order
1KG
Purity
96%
Supply Ability
500kg
Release date
2018-08-20
Career Henan Chemical Co
Product
(R)-3-Aminopyrrolidine 116183-82-5
Price
US $1.00/KG
Min. Order
1KG
Purity
96%
Supply Ability
500kg
Release date
2018-08-20

116183-82-5, (R)-3-AminopyrrolidineRelated Search:


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