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ChemicalBook > CAS DataBase List > 6-BROMO-4-HYDROXYQUINOLINE

6-BROMO-4-HYDROXYQUINOLINE

Application
Product Name
6-BROMO-4-HYDROXYQUINOLINE
CAS No.
145369-94-4
Chemical Name
6-BROMO-4-HYDROXYQUINOLINE
Synonyms
6-BROMOQUINOLIN-4-OL;6-BROMO-4-HYDROXYQUINOLINE ISO 9001:2015 REACH;SKL324;CAS:145369-94-4;BUTTPARK 23\09-03;6-BROMO-4-QUINOLINOL;6-BROMOQUINOLIN-4-ONE;4-Quinolinol, 6-bromo-;6-BROMO-4(1H)-QUINOLONE;6-BROMO-4-HYDROXYQUINOLINE
CBNumber
CB4738682
Molecular Formula
C9H6BrNO
Formula Weight
224.05
MOL File
145369-94-4.mol
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6-BROMO-4-HYDROXYQUINOLINE Property

Melting point:
283°C(lit.)
Boiling point:
370.7±22.0 °C(Predicted)
Density 
1.705±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
powder to crystal
pka
3.83±0.40(Predicted)
color 
White to Light yellow
InChI
InChI=1S/C9H6BrNO/c10-6-1-2-8-7(5-6)9(12)3-4-11-8/h1-5H,(H,11,12)
InChIKey
XKLBNOHKHRAXKK-UHFFFAOYSA-N
SMILES
N1C2C(=CC(Br)=CC=2)C(O)=CC=1
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-36/37/39
HazardClass 
IRRITANT
HS Code 
29334900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B4899
Product name
6-Bromo-4-hydroxyquinoline
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$77
Updated
2025/07/31
TCI Chemical
Product number
B4899
Product name
6-Bromo-4-hydroxyquinoline
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$281
Updated
2023/01/07
TRC
Product number
B698935
Product name
6-Bromoquinolin-4-ol
Packaging
250mg
Price
$55
Updated
2021/12/16
TRC
Product number
B698935
Product name
6-Bromoquinolin-4-ol
Packaging
500mg
Price
$65
Updated
2021/12/16
Apolloscientific
Product number
OR3631
Product name
6-Bromo-4-hydroxyquinoline
Packaging
500mg
Price
$15
Updated
2021/12/16
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6-BROMO-4-HYDROXYQUINOLINE Chemical Properties,Usage,Production

Application

6-Bromo-4-hydroxyquinoline is an important intermediate in the metallurgical, dye, polymer, and agrochemical industries. It can also be used as a disinfectant, preservative, and solvent.

Chemical Properties

Tan powder

Synthesis

98948-95-9

145369-94-4

4.1.7 Synthesis of 6-bromoquinolin-4-ol (10): 6-bromo-4-hydroxyquinoline-3-carboxylic acid (9) (5.0 g, 18.73 mmol) was placed in a 100 mL round-bottomed flask and diphenyl ether (Ph2O, 30 mL) was added. The reaction mixture was stirred at 260 °C for 2 hours. After completion of the reaction, it was cooled to 60 °C and petroleum ether (30 mL) was added to precipitate the product. The suspended solid was collected by filtration and washed sequentially with petroleum ether and ethyl acetate (EtOAc). Finally, the product was dried under reduced pressure to afford the title compound 6-bromoquinolin-4-ol (10) (3.21 g, 14.39 mmol, 77% yield) as a brown solid.ESI-MS: m/z = 224 [M + H]+.

References

[1] ChemMedChem, 2015, vol. 10, # 5, p. 836 - 849
[2] Patent: US2006/63805, 2006, A1. Location in patent: Page/Page column 9
[3] Patent: WO2012/116237, 2012, A2. Location in patent: Page/Page column 120
[4] Patent: US2015/320727, 2015, A1. Location in patent: Paragraph 0557; 0558
[5] European Journal of Medicinal Chemistry, 2015, vol. 99, p. 36 - 50

6-BROMO-4-HYDROXYQUINOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-BROMO-4-HYDROXYQUINOLINE Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
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View Lastest Price from 6-BROMO-4-HYDROXYQUINOLINE manufacturers

Career Henan Chemical Co
Product
6-BROMO-4-HYDROXYQUINOLINE 145369-94-4
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100KG
Release date
2018-12-21

145369-94-4, 6-BROMO-4-HYDROXYQUINOLINERelated Search:


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  • 6-BROMOQUINOLIN-4-OL
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  • 6-BROMO-4-QUINOLINOL
  • 6-BROMO-4-HYDROXYQUINOLINE
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  • BUTTPARK 23\09-03
  • 6-bromo-4-hyrdroxyquinoline
  • 6-Bromo-4-hydroxyquinoline ,98%
  • 6-broMoquinolin-4-ol、6-BroMo-4-hydroxyquinoline
  • 4-Quinolinol, 6-bromo-
  • 6-BROMO-4-HYDROXYQUINOLINE ISO 9001:2015 REACH
  • SKL324
  • CAS:145369-94-4
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  • ARYL HALIDE