Z-ARG-LEU-ARG-GLY-GLY-AMC

Product Name: Z-ARG-LEU-ARG-GLY-GLY-AMC
CAS No.: 167698-69-3
Chemical Name: Z-ARG-LEU-ARG-GLY-GLY-AMC
Synonyms: Z-RLRGG-AMC;Z-RLRGG-AMC Acetate;Z-ARG-LEU-ARG-GLY-GLY-AMC;Z-Arg-Leu-Arg-Gly-Gly-AMC acetate;Z-Arg-Leu-Arg-Gly-Gly-AMC (I-1690.0025);N2-[(Phenylmethoxy)carbonyl]-L-arginyl-L-leucyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)glycinamide;Glycinamide, N2-[(phenylmethoxy)carbonyl]-L-arginyl-L-leucyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
CBNumber: CB4743554
Molecular Formula: C40H56N12O9
Formula Weight: 848.95
MOL File: 167698-69-3.mol

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Z-ARG-LEU-ARG-GLY-GLY-AMC Property

Density: 1.40±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMSO: Sparingly Soluble: 1-10 mg/ml
pka: 11.02±0.46(Predicted)
form: film or powder
color: white to beige
Sequence: {Z}-Arg-Leu-Arg-Gly-Gly-{AMC}

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Chem-Impex

Product number: 32839
Product name: Z-Arg-Leu-Arg-Gly-Gly-AMCacetatesalt,98%(HPLC)
Purity: 98%(HPLC)
Packaging: 5MG
Price: $95.76
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA110572
Product name: Z-Arg-Leu-Arg-Gly-Gly-AMC acetate salt
Packaging: 10mg
Price: $114
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA110572
Product name: Z-Arg-Leu-Arg-Gly-Gly-AMC acetate salt
Packaging: 25mg
Price: $227
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA110572
Product name: Z-Arg-Leu-Arg-Gly-Gly-AMC acetate salt
Packaging: 50mg
Price: $394
Updated: 2021/12/16

Chem-Impex

Product number: 32839
Product name: Z-Arg-Leu-Arg-Gly-Gly-AMCacetatesalt,98%(HPLC)
Purity: 98%(HPLC)
Packaging: 25MG
Price: $452.2
Updated: 2021/12/16

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Z-ARG-LEU-ARG-GLY-GLY-AMC Chemical Properties,Usage,Production

Uses

Z-Arg-Leu-Arg-Gly-Gly-AMC is a peptide substrate of SARS-CoV PLpro[1].

Biological Activity

Z-RLRGG-AMC is a fluorogenic substrate for the MERS-CoV, SARS-CoV, SARS-CoV-2 papain-like protease (PLpros), deubiquitinating enzyme isopeptidase T (IPaseT) and other ubiquitin C-terminal hydrolases, which consists of the Ub and ISG15 C-terminal sequences. Z-RLRGG-AMC excitation wavelength is 340 nm, and emission wavelength is 460 nm.

References

[1] Schalk F, et, al. GNPS-guided discovery of xylacremolide C and D, evaluation of their putative biosynthetic origin and bioactivity studies of xylacremolide A and B. RSC Adv. 2021 May 24;11(31):18748-18756. DOI:10.1039/d1ra00997d
[2] ROSS L. STEIN Francesco M Zhijian Chen. Kinetic studies of isopeptidase T: modulation of peptidase activity by ubiquitin[J]. Biochemistry Biochemistry, 1995, 34 39: 12616-12623. DOI: 10.1021/bi00039a017

Z-ARG-LEU-ARG-GLY-GLY-AMC Preparation Products And Raw materials

Raw materials

Preparation Products

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Z-ARG-LEU-ARG-GLY-GLY-AMC Suppliers

China 59 France 1 Germany 1 India 1 United Kingdom 1 United States 1 Global 64

GL Biochem (Shanghai) Ltd

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Nanjing Peptide Biotech Ltd.

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Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Email: Eric@peptidego.com
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Sichuan Jisheng Biopharmaceutical Co.,Ltd.

Tel: +86-0833-2598983 +86-18086877136
Fax: +86-833-2598903
Email: Nyx-peptide@jsjpharm.cn
Country: China
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167698-69-3, Z-ARG-LEU-ARG-GLY-GLY-AMCRelated Search:

N-ALPHA-CBZ-ARG-ARG 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE Z-ARG-ARG-4-METHOXY-2-NAPHTHYLAMINE Z-ARG-ARG-ARG-4M-BETANA ACETATE SALT N-ALPHA-CBZ-ARG-ARG-PRO-PHE-HIS-STA-ILE-HIS-N-EPSILON-BOC-LYS METHYL ESTER

Z-ARG-LEU-ARG-GLY-GLY-AMC

Z-RLRGG-AMC

Glycinamide, N2-[(phenylmethoxy)carbonyl]-L-arginyl-L-leucyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-

Z-Arg-Leu-Arg-Gly-Gly-AMC (I-1690.0025)

Z-RLRGG-AMC Acetate

Z-Arg-Leu-Arg-Gly-Gly-AMC acetate

N2-[(Phenylmethoxy)carbonyl]-L-arginyl-L-leucyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)glycinamide

167698-69-3

C40H56N12O9

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