ARSENIC (III) SULFIDE Property

Melting point:

300 °C(lit.)

Boiling point:

707 °C

Density 

3.43 g/mL at 25 °C(lit.)

Flash point:

707°C

storage temp. 

Poison room

solubility 

insoluble in H2O; soluble in alkaline solutions

form 

Powder

Specific Gravity

3.43

color 

Yellow to orange

Water Solubility 

Insoluble in water. Soluble in alkali sulfides or carbonate, hot HCl

Sensitive 

moisture sensitive

crystal system

Monoclinic

Merck 

14,806

Space group

P21/n

Solubility Product Constant (Ksp)

pKsp: 21.68

Lattice constant

a/nm	b/nm	c/nm	α/o	β/o	γ/o	V/nm3
1.146	0.957	0.422	90	90.5	90	0.4628

Exposure limits

ACGIH: TWA 0.01 mg/m3
NIOSH: IDLH 5 mg/m3; Ceiling 0.002 mg/m3

CAS DataBase Reference

1303-33-9(CAS DataBase Reference)

EPA Substance Registry System

Arsenic trisulfide (1303-33-9)

Safety

Hazard Codes 

T,N

Risk Statements 

23/25-50/53

Safety Statements 

20/21-28-45-60-61

RIDADR 

UN 1557 6.1/PG 2

WGK Germany 

3

RTECS 

CG2638000

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

2813909000

Hazardous Substances Data

1303-33-9(Hazardous Substances Data)

Toxicity

mouse,LD50,intraperitoneal,215mg/kg (215mg/kg),LUNGS, THORAX, OR RESPIRATION: DYSPNEABEHAVIORAL: MUSCLE WEAKNESSGASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA",Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 28(7), Pg. 53, 1984.

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H331Toxic if inhaled

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P309IF exposed or if you feel unwell:

P310Immediately call a POISON CENTER or doctor/physician.

P311Call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

ARSENIC (III) SULFIDE Chemical Properties,Usage,Production

Description

Arsenic trisulfide is a noncombustible, odorless, yellow or orange powder or red needles (changes to adifferent “red” form at 170℃). Molecular weight= 246.04;Specific gravity: 3.43 at 20℃; Boiling point= 707℃;Freezing/Melting point= 300°327℃. Hazard Identification(based on NFPA-704 M Rating System): Health 3,Flammability 2, Reactivity 0. Insoluble in water.

Chemical Properties

Arsenic trisulfide is a noncombustible, odorless, yellow or orange powder or red needles (changes to a different “red” form @ 170 C).

Chemical Properties

Orpiment, As2S3, deep orange crystals to over 1 cm in a small group

Physical properties

Yellow or orange monoclinic crystal or powder; a red allotrope modification also known; density 3.46 g/cm³; melts at 310°C; boils at 707°C; insoluble in water; soluble in liquid ammonia and alkalies.

Occurrence

Arsenic sesquisulfide occurs in nature as the mineral orpiment. It is used as a pigment; in the manufacture of infrared-transmitting glass; in semiconductors and photoconductors; in pyrotechnics; in linoleum and oil cloth; for the removal of hairs from hides; and as a reducing agent.

Uses

Arsenic(III) sulfide is used in the treatment of acute promyelocytic leukemia. It is an inorganic photoresist used in the fabrication of photonic crystals and 3-D nanostructures. It is also used as an acousto-optic material, pigment, tanning agent and chalcogenide glass for infrared optics. Further, it is used as an analytical test for presence of dissimilatory arsenic-reducing bacteria (DARB).

Uses

manufacture of glass, particularly infrared-transmitting glass; manufacture of oil cloth, linoleum; in electrical semiconductors, photoconductors; as pigment; for depilating hides; in pyrotechnics.

Definition

Arsenic(III) sulfide (Arsenic tri-sulfide glass) is a glassy material. It is important as the window of a cell for a sample containing water.

Preparation

Arsenic sesquioxide may be prepared by heating arsenic trioxide with hydrogen sulfide:
As₂O₃ + 3 H₂S → As₂S₃ + 3 H₂O
Alternatively, it may be precipitated out from a solution of arsenous acid or arsenic trioxide in dilute hydrochloric acid by passing hydrogen sulfide into the solution:
2H₃AsO₃ + 3H₂S → As₂S₃ + 6H₂O.

General Description

A yellow or red crystalline solid or powder. Combustible. Insoluble in water. Toxic by inhalation (dust) and ingestion.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

ARSENIC (III) SULFIDE is dissolved by alkalis and by hydrochloric acid (slowly). Decomposed by nitric acid. May react with oxidizing agents to generate heat and products that may be flammable, combustible, or otherwise reactive. The reactions may be violent. ARSENIC (III) SULFIDE reacts with concentrated solutions of chloric acid with incandescence [Mellor Supp. II Part I:584 1956]. Generates toxic gaseous hydrogen sulfide on contact with acids.

Health Hazard

(Acute and sub-acute poisoning are not common.) Repeated inhalation causes irritation of nose, laryngitis, mild bronchitis. Ingestion causes weakness, loss of appetite, gastrointestinal disturbances, peripheral neuritis, occasional hepatitis. Contact with eyes causes irritation. Irritates skin, especially where moist; if not treated, may cause ulceration.

Fire Hazard

Combustible material: may burn but does not ignite readily. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

Industrial uses

As₂S₃ (orpiment) and As₂S₂ (realgar) have been used as early as 2000 BC as drugs, for example, to cure cancerous tumours, ulcers and other diseases of the time. Later, Galen (130 200 AD) recommended the application of a paste of arsenic sulfide against ulcers.

Safety Profile

Confirmed human carcinogen with experimental tumorigenic data. A poison. Reacts violently with H202, (m03 + S). When heated to decomposition or on contact with acid or acid fumes it emits highly toxic fumes of S02, H2S, and As. Reacts with water or steam to emit toxic and flammable vapors.

Toxicology

Arsenic trisulfide is obtained by fusing arsenic trioxide with sulfur is marketed as orpiment. Or piment always contains unchanged arsenic tri oxide and, unlike the pure sulfide, is poisonous.

Potential Exposure

Arsenic trisulfide is used in the manufacture of glass, oil cloth, linoleum, electrical semiconductors, fireworks and used as a pigment.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit. Note to physician: For severe poisoning BAL [British AntiLewisite, Dimercaprol, dithiopropanol (C3H8OS2)] has beenused to treat toxic symptoms of certain heavy metals poisoning including arsenic. Although BAL is reported to have alarge margin of safety, caution must be exercised, becausetoxic effects may be caused by excessive dosage. Most canbe prevented by premedication with 1-ephedrine sulfate(CAS: 134-72-5). For milder poisoning penicillamine (notpenicillin) has been used, both with mixed success. Sideeffects occur with such treatment and it is never a substitutefor controlling exposure. It can only be done under strictmedical care.

storage

Color Code—Blue: Health Hazard/Poison: Store ina secure poison location. Prior to working with this chemicalyou should be trained on its proper handling and storage.Avoid contact with the incompatible materials cited above.A regulated, marked area should be established where thischemical is handled, used, or stored in compliance withOSHA Standard 1910.1045.

Shipping

UN1557 Arsenic compounds, solid, n.o.s. inorganic, including arsenates, n.o.s.; arsenites, n.o.s.; arsenic sulfides, n.o.s.; and organic compounds of arsenic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Incompatibilities

A strong reducing agent; avoid contact with oxidizers (such as perchlorates, peroxides, permanganates, chlorates, and nitrates) and potassium nitrate mixed with sulfur, since violent reactions occur. Water contact forms hydrogen sulfide. Incompatible with acids, halogens. Contact with acids or acid mists releases deadly arsine gas.

Waste Disposal

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.