11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE

Product Name: 11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE
CAS No.: 1482-50-4
Chemical Name: 11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE
Synonyms: dihydrocortisol;5β-Dihydrocortiso;5B-Dihydrocortisol;52-Dihydrocortisol;5β-Dihydrocortisol;5-BETA-DIHYDROCORTISOL;21-Di[methylenebis(oxy)] 5α5B-pregnane-11B-17A-21-triol-3-20-dione;5β-Pregnane-11β,17α,21-triol-3,20-dione;5β-PREGNAN-11β, 17, 21-TRIOL-3, 20-DIONE
CBNumber: CB4757474
Molecular Formula: C21H32O5
Formula Weight: 364.48
MOL File: 1482-50-4.mol

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11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE Property

Melting point:: >173°C (dec.)
Boiling point:: 544.5±50.0 °C(Predicted)
Density: 1.249±0.06 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 12.50±0.70(Predicted)
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SMB01348
Product name: Dihydrocortisol
Purity: ≥95% (HPLC)
Packaging: 25MG
Price: $108
Updated: 2025/07/31

Sigma-Aldrich

Product number: SMB01348
Product name: Dihydrocortisol
Purity: ≥95% (HPLC)
Packaging: 100MG
Price: $241
Updated: 2025/07/31

TRC

Product number: D448595
Product name: 5β-Dihydrocortisol
Packaging: 1g
Price: $1390
Updated: 2021/12/16

ChemScene

Product number: CS-0146622
Product name: 5β-Dihydrocortisol
Packaging: 5mg
Price: $280
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: SHG0020377
Product name: 5-BETA-PREGNAN-11BETA,17ALPHA,21-TRIOL-3,20-DIONE
Purity: 95.00%
Packaging: 5MG
Price: $450.97
Updated: 2021/12/16

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11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE Chemical Properties,Usage,Production

Uses

5β-Dihydrocortisol, is a derivative of Cortisol (H714615), which is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland.

Definition

ChEBI: 5beta-dihydrocortisol is a 17alpha-hydroxy-C21-steroid that is cortisol in which the 4-5 double bond has undergone formal hydrogenation to give the corresponding 5beta- steroid. It is a 21-hydroxy steroid, a 17alpha-hydroxy-C21-steroid, an 11beta-hydroxy steroid, a 3-oxo-5beta-steroid, a primary alpha-hydroxy ketone, a triol, a secondary alcohol, a diketone, a 20-oxo steroid and a tertiary alpha-hydroxy ketone.

in vivo

5β-Dihydrocortisol (0.1-1.0%; 18 d) potentiates the action of topically applied Dexamethasone (0.06%) in raising the intraocular pressure (IOP) in young rabbits^[3].

11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE Suppliers

China 18 India 1 South Korea 1 Switzerland 1 United Kingdom 1 United States 8 Global 30

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1482-50-4, 11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONERelated Search:

11-BETA-HYDROXYPREGNANEDIONE 5-BETA-PREGNAN-17,21-DIOL-3,20-DIONE 11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE 5B-PREGNANE-11B,21-DIOL-3,20-DIONE 5-BETA-DIHYDRO-17-HYDROXYPROGESTERONE PREGNANEDIONE 5-BETA-DIHYDROCORTISOL ACETATE 2-DECALONE

11,17,21-trihydroxy-,(5beta,11beta)-pregnane-20-dione

11-beta,17,21-trihydroxy-5-beta-pregnane-20-dione

11-beta,17,21-trihydroxy-5-beta-pregnane-3,20-dione

dihydrocortisol

11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE

5-BETA-PREGNAN-11-BETA, 17,21-TRIOL-3,20-DIONE

5BETA-PREGNAN-11BETA,17ALPHA,21-TRIOL-3,20-DIONE

5-BETA-DIHYDROCORTISOL

5B-pregnane-11B-17A-21-triol-3-20-dione

(5R,8S,9S,10S,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-one

5B-Dihydrocortisol

5β-Pregnane-11β,17α,21-triol-3,20-dione

52-Dihydrocortisol

21-Di[methylenebis(oxy)] 5&alpha

5β-Dihydrocortisol

Pregnane-3,20-dione, 11,17,21-trihydroxy-, (5β,11β)-

5β-PREGNAN-11β, 17, 21-TRIOL-3, 20-DIONE

11β,17α,21-Trihydroxy-5β-Pregnane-3, 20-Dione

5β-Dihydrocortiso

1482-50-4

Pharmaceuticals, Intermediates & Fine Chemicals, Steroids